TABLE 2

Bivariate Predictors of TSB Reaching the Exchange Transfusion Level Within 48 Hours

CharacteristicsTSB Level Reached in <48 h at Which Exchange Transfusion Recommended
No. (%) of CohortNo. (%) With OutcomeORPa
Gender
    Female9672 (43)68 (0.70)Ref
    Male12875 (57)119 (0.92)1.3.06
Gestational age, wk
    351522 (7)16 (1.10)3.09.008
    362158 (10)50 (2.20)6.88<.001
    372700 (12)54 (2.00)5.92<.001
    383918 (17)23 (0.59)1.71.15
    395302 (24)21 (0.40)1.15.64
    404954 (22)17 (0.34)Ref
    ≥411993 (9)6 (0.30)0.88.76
Race
    White9145 (41)72 (0.79)Ref
    Asian6008 (27)47 (0.78)0.99.99
    Hispanic4972 (22)43 (0.88)1.13.53
    Black1039 (5)16 (1.54)1.97.008
    Other1002 (4)4 (0.40)0.51.16
    Unknown381 (2)4 (1.05)1.34.29
AAP risk group
    Low14591 (65)32 (0.22)Ref
    Medium7716 (34)131 (1.70)7.86<.001
    High240 (1)24 (10.0)50.6<.001
Age at qualifying TSB level, h
    <242196 (10)44 (2.00)1.63.10
    24 to <486801 (30)84 (1.24)Ref
    48 to <726563 (29)36 (0.55)0.44.001
    72 to <964665 (21)15 (0.32)0.26<.001
    ≥962322 (10)8 (0.34)0.28<.001
TSB minus AAP phototherapy threshold, mg/dL
    −3 to less than −25750 (26)3 (0.05)0.06<.001
    −2 to less than −15343 (24)12 (0.22)0.27<.004
    −1 to <04347 (19)21 (0.48)0.59.05
    0 to <13186 (14)26 (0.82)Ref
    1 to <22347 (10)55 (2.34)2.92<.001
    2 to <31574 (7)70 (4.45)5.66<.001
Hospital phototherapy
    Not within 8 h17296 (77)146 (0.84)Ref
    Within 8 h5251 (23)41 (0.78)0.80.66
Home phototherapy
    Not within 1 d22167 (98)186 (0.84)Ref
    Within 1 d380 (2)1 (0.26)0.29.25
  • Ref indicates reference group for OR; TSB indicates total serum bilirubin adjusted for clustering by hospital.

  • a All of the P values were calculated from χ2 test.