TABLE 3

Ages of Pubertal Events From Studies of US Girls

StudyMean/Mediana Age of Attainment of a Stage, y (SD, SE, or FL/CLb)
B2B3B4B5PH2PH3PH4PH5Menarche
Fels Study; Reynolds and10.8(1.1)11.4 (IMR)12.2 (NR)13.7 (IMR)11.0(1.1)11.9 (NR)12.5 (IMR)13.9 (IMR)12.9(1.4) white
Wines13 (1948)
Guidance Study;10.6(1.2)11.2(1.1)NDC13.9 (0.9)11.6 (0.9)12.5(1.0)13.2 (0.9)NF;d12.8(1.1)
Ni col son and Hanley14 (1953)
NHES l,ll,and III; MacMahon63 (1973)IMDIMDIMDIMDIMDIMDIMDIMDI';: 12,73 (1,386) white; 12,85 (1,534) black; II and III6 12,80 (0,41) white; 12,52 (0.111) black
NHES II and III; Anderson etal3 (2003)IMDIMDIMDIMDIMDIMDIMDIMD12.75 (12.69-12.82) all; 12.80 (12.73-12.87) white; 12.48(12.28-12.67) black
NHES III
Sun etal65 (2005)IMD11.52 (9.98-12.15) white; IMS for blackf12.78 (12.49-13.02) white; 11.46 (10.09-12.21) black15.47 (15.26-15.69) white; 14.29 (13.80-14.71) blackIMDIMS for whited; NS for blacks12.74(12.54-12.92) white; 11.85 (10.97-12.39) black14.02 (13.58-14.39) white; 14.02 (13.58-14.39) blackIMD
Lee17 (1980)11.2(1.6)12.4(1.2)13.1 (0.7)14.5(1.6)11.9(1.5)12.7 (0.5)13.4(1.2)14.6(1.1)13,3 (1.3) A, 1
Bogalusa Heart Study; Foster etal61 (1977)10,37 (0,105) white; 10,22 (0,125) black11,60 (0,09) white; 10,91 (0,12) blackNR9NR910,86 (0,095) white; 1043 (0425) black11,66 (0,09) white; 10,91 (04 2) blackNRhNF;h1973-1974:12.69 (0.085) white; 12.83 (0.11) black
HHANES; Villarreal et al6410.95 (10.93-11.31)12.16(12.00-12.44)13.86 (13.57-14.13)15.10(14.78-15.36)11.32(11.19-11.61)12.44(12.25-12.65)14.07 (13.74-14.26)15.50 (15.11-15.65)IMD
(1989)'Mexican AmericanMexican AmericanMexican AmericanMexican AmericanMexican AmericanMexican AmericanMexican AmericanMexican American
HHANES; Sun et al65 (2005)IMD11.98(11.52-12.4) Mexican American13.72 (13.46-13.98) Mexican American14.97 (14.70-15.25) Mexican AmericanIMD12.24(11.67-12.76) Mexican American13.92 (13.68-14.16) Mexican American15.27 (15.01-15.54) Mexican AmericanIMD
Bogalusa Heart Study; Freedman et al4 (2002)IMDIMDIMDIMDIMDIMDIMDIMD1973-19741: 12.7 (12.6-12.9) white; 12.9(12.7-13.1) black; 1992-19941: 12.5(12.4-12.8) white; 12.1 (11.9-12.3) black
PROS; Herrnan-Giddens et al5 (1997)9,96 (1,82) white; 8,87 (1.93) black11,30 (1,42) white; 10,19(1,42) blackIMDIMD10.51 (1.67) white; 8.78(2.00) black11,53 (1,21) white; 10,35 (1.63) blackIMDIMD12.88 (1.20) white; 12,16(1,21) black
IMHANES III; Wu et al47 (2002)10.3(10.0-10.5) white; 9.5 (93-9.8) black; 97(9.4-9.9) Mexican AmericanIMDIMDIMD10.6(10.4-10.9) white; 9.5 (9.2-9.8) black; 10.3 (10.1-10.6) Mexican AmericanIMDIMDIMD12.6(12.4-12.8) white; 12.2(12.0-12.4) black; 12.2 (12.0-12.5)
Mexican Arnericank
NHANES III; Sun et al4610.38(10.11-10.65)11.75 (11.49-12.02)13.29 (12.97-13.61)15.47(15.04-15.94)10.57(10.29-10.85)11.80(11.54-12.07)13.00 (12.71-13.30)16.33 (15.86-16.88)IMD
(2002)l,mwhite; 9.48 (9.14-9.76) black; 9.80 (0-1178n) Mexican Americanwhite; 10.79 (10.50-11.08) black; 11.43 (8.64-14.50) Mexican Americanwhite; 12.24 (11.87-12.61) black; 13.07 (12.79-13.36) Mexican Americanwhite; 13.92 (13.57-14.29) black; 14.70 (14.37-15.04) Mexican Americanwhite; 9.43 (9.05-9.74) black; NS for Mexican American0white; 10.57 (10.30-10.83) black; 11.70 (11.14-12.27) Mexican Americanwhite; 11.90 (11.38-12.42) black; 13.19 (12.88-13.52) Mexican Americanwhite; 14.70 (14.32-15.11) black; 16.30 (15.90-16.76) Mexican American
NHANES III; Chumlea et al46 (2003)NDNDNDNDNDNDNDND12.43 (12.33-12.53) all; 12.55 (12.31-12.79) white; 12.06 (11.84-12.28) black; 12.25 (12.04-12.46) Mexican American
NHANES III; Anderson et al3 (2003)NDNDNDNDNDNDNDND12.54(12.44-12.64) all; 12.60 (12.48-12.71) white; 12.14 (11.87-12.39) black
NHANES III; Sun et al65 (2005)ND11.82 (10.49-12.32) white; NS for blacks; NS for Mexican Americans12.90 (12.18-13.39) white; 11.46 (9.73-12.31) black; 13.04
(12.70-13.37) Mexican American
15.16(14.61-15.71) white; 13.54 (12.77-14.10) black; 14.74 (14.42-15.09) Mexican AmericanNDNS for whites; 11.48 (7.54-12.24) black; 11.65
(11.01-12.15) Mexican American
12.73 (12.08-13.16) white; NS for blacks; 13.15 (12.77-13.53) Mexican American16.13 (15.55-16.92) white; 14.29 (13.62-14.84) black; 16.24 (15.83-16.73) Mexican AmericanND
  • ND, not determined; NS, not shown in this table; CL, 95% confidence limits; FL, fiducial limits.

  • a Means and medians are considered comparable values because the ages for various pubertal markers are typically normally distributed.

  • b See references for details.

  • c Nicolson and Hanley14 used a 4-stage breast development scale in which B3 was equivalent to Tanner B3 and B4 was equivalent to Tanner B5. Thus, Tanner B4 was not determined.

  • d Not reported because PH5 was considered by the authors to be unreliable as a result of the interrater agreement score.

  • e Mean age data were restricted to women aged 18 to 34 years in cycle I; women were born 1926 to 1944 and thus were peripubertal ages (10-15 years) —1936-1956.

  • f Data from cycles II and III were combined, and the analysis was limited to ages 11 to 14 years.

  • g Not shown in this table because the FLs were labeled “unstable” by the authors.

  • h Foster et al61 only reported median ages for transition into B2, B3, PH2, and PH3 because of the “limited age range,” 5 to 14 years, of their population.

  • i Villarreal etal64 calculated percentages of girls in a given stage by age, means for being in a stage, means (from probit analysis), and medians (from Spearrnan-Karber analysis) for entry into a stage. Means for entry into a stage are presented here for comparison with the other studies.

  • j Freedman etal4 reported data from 7 cohorts assessed between 1973 and 1994. Because of space limitations, only median ages are shown for the first (1973-1974) and last (1992-1994) cohorts studied.

  • k Wu et al47 calculated mean rnenarcheal age separately for current status and recalled age. Mean ages from current status data are shown.

  • l Sun et al45 calculated means for “age in a stage” and medians for “age at entry” into a stage. Medians for “age at entry” are reported here for comparison with other studies that looked at age of attainment.

  • m FLs were computed at 98.3% CLs to adjust for multiple comparisons between racial/ethnic groups.

  • n The left side FL ofO is likely attributable to the small sample size for Mexican Americans.

  • o Not shown in this table because the authors did not report the FL because of the small sample size for Mexican Americans.