TABLE 4

aHRsa for Select Covariates Among Children With Down Syndrome (n = 16 418) by Age at Follow-up From 10 US Regions, 1983–2003

1 mo2–12 mo1–5 y6–10 y11–20 yOverall
Race/ethnicity
 WhiteReferentReferentReferentReferentReferentReferent
 Blacks1.0 (0.7–1.5)1.4 (1.2–1.8)b1.9 (1.4–2.6)b2.0 (1.0–4.0)b1.7 (0.6–5.1)1.4 (1.0–1.6)
 Hispanics0.8 (0.6–1.0)b1.0 (0.9–1.2)0.8 (0.6–1.0)0.6 (0.3–1.2)1.7 (0.6–4.7)0.8 (0.7–0.9)b
 Other1.3 (0.8–2.0)1.3 (1.0–1.7)1.2 (0.8–2.0)2.4 (1.1–5.4)b1.9 (0.4–8.0)1.3 (1.1–1.6)b
Birth wt
 ≥2500ReferentReferentReferentReferentReferentReferent
 1500–24992.4 (1.8–3.2)b1.9 (1.7–2.3)b1.4 (1.1–1.9)b1.2 (0.7–2.4)1.3 (0.5–3.1)1.8 (1.6–2.0)b
 <150023.8 (18.4–30.7)b6.9 (5.6–8.6)b2.1 (1.2–3.9)b1.1 (0.2–8.2)8.5 (2.5–28.6)b8.5 (7.3–9.8)b
Maternal age
 <35ReferentReferentReferentReferentReferentReferent
 ≥35 y1.0 (1.0–1.0)1.0 (1.0–1.0)1.0 (1.0–1.0)1.0 (1.0–1.0)1.0 (0.9–1.0)1.0 (1.0–1.0)
CHD, yes vs no (referent)0.8 (0.6–1.2)4.6 (3.9–5.4)b4.0 (3.1–5.2)b1.9 (1.1–3.2)b2.0 (1.0–4.0)b2.7 (2.4–3.0)b
Birth cohort
 1983–1989ReferentReferentReferent
 1990–19960.9 (0.6–1.2)1.0 (0.8–1.2)0.6 (0.5–0.8)b
 1997–20030.8 (0.5–1.1)0.5 (0.4–0.6)b0.5 (0.4–0.7)b
  • Birth wt reference group is ≥2500. Survival probability among non-Hispanic blacks, Hispanic, and other was compared with the survival probability among non-Hispanic whites. —, no estimates were produced because of small numbers.

  • a Adjusted for race/ethnicity, birth wt, maternal age and education, presence of a CHD, birth period, and region of birth.

  • b Statistical difference in survival probabilities between category stratum and the referent group.