Overview of Studies
| Characteristic | RCTs (n = 5) | Prospective Case Series (n = 2) | Retrospective Case Series (n = 1) | Total Literature (N = 8a) |
|---|---|---|---|---|
| Intervention | ||||
| Antipsychoticsa | 3 | 0 | 0 | 3 |
| SRIsa | 2 | 2 | 1 | 5 |
| Opioid receptor antagonist | 1 | 0 | 0 | 1 |
| Treatment duration, mo | ||||
| >1 to ≤3 | 4 | 2 | 0 | 6 |
| >3 to ≤6 | 1 | 0 | 0 | 1 |
| >6 to ≤12 | 0 | 0 | 1 | 1 |
| Study population | ||||
| United States | 3 | 2 | 1 | 6 |
| Europe | 1 | 0 | 0 | 1 |
| Other | 1 | 0 | 0 | 1 |
| Total participants | 172 | 77 | 23 | 272 |
↵a One study assessed both an antipsychotic agent and an SRI.