TABLE 3

Overview of Studies

CharacteristicRCTs (n = 5)Prospective Case Series (n = 2)Retrospective Case Series (n = 1)Total Literature (N = 8a)
Intervention
 Antipsychoticsa3003
 SRIsa2215
 Opioid receptor antagonist1001
Treatment duration, mo
 >1 to ≤3 4206
 >3 to ≤6 1001
 >6 to ≤120011
Study population
 United States3216
 Europe1001
 Other1001
Total participants1727723272
  • a One study assessed both an antipsychotic agent and an SRI.