TABLE 1

Inclusion and Exclusion Criteria

CategoryCriteria
Study populationAdolescents or young adults (ages 13–30 years) with ASD (autistic disorder, Asperger syndrome, PDD-NOS) or families/caregivers of individuals with ASD between the ages of 13 and 30 years
InterventionsInterventions aimed at ameliorating core symptoms of ASD, affecting independent functioning, adaptive behavior, or the transition process, or targeting family outcomes
ComparatorsPlacebo
Other intervention
OutcomesSocial skills/interaction, language and communication, repetitive and other maladaptive behaviors, motor outcomes, psychological distress, adaptive skills development, academic skills development, and family outcomes, including family distress and family satisfaction
Time periodStudies published from 1980–present with no limits on timing of outcomes
SettingAny setting, including educational, residential, and clinic
Publication languagesEnglish only
Admissible evidence (study design and other criteria)
 Admissible designControlled trials, observational studies including prospective and retrospective cohort studies, prospective and retrospective case series
 Study sizeAt least 20 total individuals between 13 and 30 years of age with ASD or family members of such individuals
 Other criteriaOriginal research studies that provide sufficient detail regarding methods and results to enable use and adjustment of the data and results
Patient populations must include adolescents or young adults (13–30 years of age) with ASD or families/caregivers of individuals with ASD between the ages of 13 and 30 years
Studies must address 1 or more of the following: (1) treatment modality aimed at modifying ASD core symptoms, common comorbidities, family-related outcomes, or assisting with transitional issues; and (2) outcomes (including harms) related to interventions for ASD
Studies must include extractable data on relevant outcomes, including data presented in text or tables (versus solely in figures)
Studies must present aggregate data (versus only data for each individual participant)
  • PDD-NOS, pervasive developmental disorder–not otherwise specified.