TABLE 6

Risk Ratios and Adjusted Risk Ratios of Exposure to Anesthesia Before Age 3 and Disability on Neuropsychological Testing at Age 10

Disability
Unadjusted, RR (95% CI)Adjusted, aRRa (95% CI)
Overall cohort
 CELF Total 2.31 (1.56–3.41)2.11 (1.42–3.14)
 CELF Receptive2.15 (1.37–3.37)1.87 (1.20–2.93)
 CELF Expressive1.84 (1.21–2.80)1.72 (1.12–2.64)
 CPM Total1.65 (1.12–2.43)1.69 (1.13–2.53)
Number of exposures
 CELF total
  Unexposed (0)ReferenceReference
  Single exposure (1)2.82 (1.74–4.57)2.36 (1.47–3.79)
  Multiple exposure (≥2)2.49 (1.05–5.88)2.68 (1.07–6.72)
 CELF receptive
  Unexposed (0)ReferenceReference
  Single exposure (1)2.99 (1.72–5.19)2.41 (1.40 – 4.17)
  Multiple exposure (≥2)3.29 (1.37–7.89)3.52 (1.38 – 9.00)
 CELF expressive
  Unexposed (0)ReferenceReference
  Single exposure (1)1.80 (1.03–3.15)1.53 (0.88–2.66)
  Multiple exposure (≥2)2.27 (0.96–5.35)2.35 (0.97–5.70)
 CPM total
  Unexposed (0)ReferenceReference
  Single exposure (1)1.81 (1.12–2.94)1.73 (1.04–2.88)
  Multiple exposure (≥2)1.78 (0.76–4.15)1.92 (0.81–4.55)
  • RR, risk ratio.

  • a Adjusted risk ratios (aRR) adjusted for sex, low birth weight (<2500 g), race, income, and maternal education.