TABLE 1

Percent of Subjects With Acute Allergic Reactions According to Baseline Features

N% of Subjects With Reactions
AllMilkEggPeanutOther
Overall
 All subjects51271.742.430.313.535.2
Age, mo
 3–56561.538.521.513.832.3
 6–812869.537.524.210.938.3
 9–1218276.950.034.111.537.9
 13–1513771.538.735.018.229.9
Gender
 Boy34574.245.829.913.633.0
 Girl16766.535.331.113.239.5
Race
 White38072.443.932.112.133.7
 African American7867.935.930.817.938.5
 Asian4465.940.915.915.931.8
 Other1010040.020.020.080.0
Sitea
 National Jewish Health9977.840.434.318.234.3
 Duke University10347.633.011.75.86.8
 Johns Hopkins University10970.645.924.89.238.5
 Mount Sinai Medical Center10780.443.931.811.258.9
 University of Arkansas9483.048.951.124.536.2
Baseline no. of food allergiesa
 None (no milk, no egg)17366.528.326.013.337.6
 1 (either milk or egg)27872.345.029.513.733.1
 2 (both milk and egg)5383.071.745.311.335.8
Household incomea
 <$50 0008674.439.543.019.833.7
 $50 000–$99 00013566.740.025.213.330.4
 ≥$100 00021575.348.427.010.739.1
Maternal education
 High school or less5669.630.441.121.430.4
 Some college/college degree24574.344.527.813.135.9
 Graduate degree20869.242.830.311.535.6
Paternal educationa
 High school or less9074.437.844.422.233.3
 Some college/college degree20975.145.528.713.436.8
 Graduate degree20668.942.226.29.735.0
Baseline milk IgE, kUA/Lb
 <0.3519452.113.425.814.425.8
 ≥0.35–211173.939.634.210.832.4
 ≥2–56479.751.637.515.640.6
 ≥513493.381.328.412.747.0
Baseline egg IgE, kUA/Lb
 <0.3512953.532.613.24.722.5
 ≥0.35–211962.230.323.59.230.3
 ≥2–58182.748.143.218.530.9
 ≥517485.654.640.220.148.9
Baseline peanut IgE, kUA/Lb
 <0.3519857.632.323.24.523.2
 ≥0.35–210571.441.030.511.437.1
 ≥2–56078.341.741.716.736.7
 ≥514087.957.133.625.748.6
Baseline atopic dermatitis
 None4161.043.917.14.924.4
 Mild5072.046.036.06.026.0
 Moderate25870.944.631.414.734.1
 Severe16375.537.430.116.042.3
Have siblings
 No22375.344.835.014.333.2
 Yes28968.940.526.612.836.7
Breastfeeding history
 Never7375.341.143.820.531.5
 Yes, currently17770.149.224.38.538.4
 Yes, but no longer breastfeeding26271.838.230.514.934.0
Parental history of atopy
 Neither parent7566.746.729.312.028.0
 1 parent20568.838.030.212.735.1
 Both parents22375.844.429.614.338.1
  • kUA/L, kilounits of antibody per liter.

  • a P value from Poisson regression for all reactions was <.0005.

  • b P value from Poisson regression was <.0001 for the following risk factor analyses: baseline milk IgE for milk reactions, baseline egg IgE for egg reactions, and baseline peanut IgE for peanut reactions.