RT Journal Article
SR Electronic
T1 Insulin-Dependent Diabetes Mellitus in 2 Male African American Children After Kawasaki Disease
JF Pediatrics
JO Pediatrics
FD American Academy of Pediatrics
SP e27
OP e27
DO 10.1542/peds.110.2.e27
VO 110
IS 2
A1 Bhowmick, Samar K.
A1 Estrada, Benjamin
A1 Rettig, Kenneth R.
YR 2002
UL http://pediatrics.aappublications.org/content/110/2/e27.abstract
AB Two children with insulin-dependent diabetes mellitus (IDDM) presented with diabetic ketoacidosis within 4 months of being diagnosed with Kawasaki disease (KD). Both patients were African American males younger than 4 years of age. Immune markers associated with the autoimmune cause of diabetes were not detectable in these patients at the time of diagnosis with IDDM. In 1 patient, the immune markers were repeated 6 months after diagnosis but remained negative. Both patients currently require ∼1 unit of insulin/kg/d. Occurrence of IDDM after KD is rare; we could find no such reports in the English literature. The cause of diabetes in these 2 patients remains elusive, as does the cause of KD.