PT  - JOURNAL ARTICLE
AU  - Castro, Roberta Esteves Vieira de
AU  - Sousa, Carolina da Cunha
AU  - de Magalhães-Barbosa, Maria Clara
AU  - Prata-Barbosa, Arnaldo
AU  - Cheniaux, Elie
TI  - Ranitidine-Induced Delirium in a 7-Year-Old Girl: A Case Report
AID  - 10.1542/peds.2018-2428
DP  - 2019 Feb 01
TA  - Pediatrics
PG  - e20182428
VI  - 143
IP  - 2
4099  - http://pediatrics.aappublications.org/content/143/2/e20182428.short
4100  - http://pediatrics.aappublications.org/content/143/2/e20182428.full
SO  - Pediatrics2019 Feb 01; 143
AB  - Ranitidine is a histamine-2 blocker commonly prescribed in PICUs for the prophylaxis of gastrointestinal bleeding and stress ulcers. However, it can be associated to central nervous system side effects, such as delirium, in adults. We present the first case of a child presenting delirium possibly caused by anticholinergic toxidrome secondary to the use of ranitidine, resolving after drug discontinuation. With this case report, we reinforce that a wide variety of clinical conditions can trigger delirium and that the best therapeutic approach is to minimize risk factors.