RT Journal Article SR Electronic T1 Prospective Association of Common Eating Disorders and Adverse Outcomes JF Pediatrics JO Pediatrics FD American Academy of Pediatrics SP e289 OP e295 DO 10.1542/peds.2011-3663 VO 130 IS 2 A1 Field, Alison E. A1 Sonneville, Kendrin R. A1 Micali, Nadia A1 Crosby, Ross D. A1 Swanson, Sonja A. A1 Laird, Nan M. A1 Treasure, Janet A1 Solmi, Francesca A1 Horton, Nicholas J. YR 2012 UL http://pediatrics.aappublications.org/content/130/2/e289.abstract AB OBJECTIVE: Anorexia nervosa and bulimia nervosa (BN) are rare, but eating disorders not otherwise specified (EDNOS) are relatively common among female participants. Our objective was to evaluate whether BN and subtypes of EDNOS are predictive of developing adverse outcomes.METHODS: This study comprised a prospective analysis of 8594 female participants from the ongoing Growing Up Today Study. Questionnaires were sent annually from 1996 through 2001, then biennially through 2007 and 2008. Participants who were 9 to 15 years of age in 1996 and completed at least 2 consecutive questionnaires between 1996 and 2008 were included in the analyses. Participants were classified as having BN (≥weekly binge eating and purging), binge eating disorder (BED; ≥weekly binge eating, infrequent purging), purging disorder (PD; ≥weekly purging, infrequent binge eating), other EDNOS (binge eating and/or purging monthly), or nondisordered.RESULTS: BN affected ∼1% of adolescent girls; 2% to 3% had PD and another 2% to 3% had BED. Girls with BED were almost twice as likely as their nondisordered peers to become overweight or obese (odds ratio [OR]: 1.9 [95% confidence interval: 1.0–3.5]) or develop high depressive symptoms (OR: 2.3 [95% confidence interval: 1.0–5.0]). Female participants with PD had a significantly increased risk of starting to use drugs (OR: 1.7) and starting to binge drink frequently (OR: 1.8).CONCLUSIONS: PD and BED are common and predict a range of adverse outcomes. Primary care clinicians should be made aware of these disorders, which may be underrepresented in eating disorder clinic samples. Efforts to prevent eating disorders should focus on cases of subthreshold severity.Abbreviations:BED — binge eating disorderBN — bulimia nervosaCI — confidence intervalDSM-IV — Diagnostic and Statistical Manual of Mental Disorders, Fourth EditionDSM-5 — fifth edition of the Diagnostic and Statistical Manual of Mental DisordersEDNOS — eating disorder not otherwise specifiedGEE — generalized estimating equationsGUTS — Growing Up Today StudyMRFS — McKnight Risk Factor SurveyOR — odds ratioPD — purging disorder