RT Journal Article
SR Electronic
T1 Recurrent Parotitis as a Presentation of Primary Pediatric Sjögren Syndrome
JF Pediatrics
JO Pediatrics
FD American Academy of Pediatrics
SP e179
OP e182
DO 10.1542/peds.2011-0716
VO 129
IS 1
A1 Baszis, Kevin
A1 Toib, Dana
A1 Cooper, Megan
A1 French, Anthony
A1 White, Andrew
YR 2012
UL http://pediatrics.aappublications.org/content/129/1/e179.abstract
AB Parotitis is a common condition seen in the pediatric population, usually as an isolated occurrence associated with viral or bacterial infection. The differential diagnosis expands when recurrent parotitis is encountered. One etiology is primary pediatric Sjögren syndrome (SS), an autoimmune condition typically associated with dryness of the eyes and mouth in adults. Pediatric patients often present with isolated recurrent bilateral parotitis, however, and we describe 4 such cases in children aged 9 to 17 years at presentation. Despite lack of ocular complaints, 3 of these patients had ocular findings on ophthalmologic exam. Our patients also exhibited classic laboratory abnormalities, including positive antinuclear antibody, SS A, and SS B antibodies; presence of rheumatoid factor; and hypergammaglobulinemia. Consideration of SS in the child with recurrent parotitis is important for timely and appropriate referral and treatment. We review the differential diagnosis of parotitis in children as well as the salient features of pediatric SS.Abbreviations:ANA — antinuclear antibodyESR — erythrocyte sedimentation rateRF — rheumatoid factorSLE — systemic lupus erythematosusSS — Sjögren syndrome