PT  - JOURNAL ARTICLE
AU  - Schwartz, Robert
TI  - Comments From Another Student of Gamble and Darrow on Fluids
DP  - 1996 Aug 01
TA  - Pediatrics
PG  - 314--314
VI  - 98
IP  - 2
4099  - http://pediatrics.aappublications.org/content/98/2/314.1.short
4100  - http://pediatrics.aappublications.org/content/98/2/314.1.full
SO  - Pediatrics1996 Aug 01; 98
AB  - Holliday's historical review of fluid and electrolyte pathophysiology represents thoughtful and timely comments. I agree with his thoughts as applied to diarrheal dehydration. However, his strong advocacy of oral rehydration therapy (ORT) in diarrheal dehydration should not be interpreted as relevant to other disorders of fluid and electrolyte pathophysiology. The successful use of ORT in the third world, coincident with scientific understanding of cholera toxin effects on sodium-glucose transport in the intestine, has provided both a scientific and practical basis for practical recommendations.