PT  - JOURNAL ARTICLE
AU  - Markowitz, Morri E.
AU  - Weinberger, Howard L.
TI  - Immobilization-Related Lead Toxicity in Previously Lead-Poisoned Children
DP  - 1990 Sep 01
TA  - Pediatrics
PG  - 455--457
VI  - 86
IP  - 3
4099  - http://pediatrics.aappublications.org/content/86/3/455.short
4100  - http://pediatrics.aappublications.org/content/86/3/455.full
SO  - Pediatrics1990 Sep 01; 86
AB  - In the late 1970s more than half a million children younger than 7 years of age had elevated blood lead concentrations (>1.45 µmol/L, or 30 µg/dL, the clinical cutoff for an elevated lead level at that time.1 Despite a declining incidence of new cases since then, a large reservoir of previously exposed children must exist. (Sedlis M. 1989. Personal communication). More than two thirds of a child's lead burden is contained in the skeleton.2 In one experimental model, a small fraction of the bone lead content is in a readily exchangeable pool with blood and soft tissues.3 The majority of the lead in bone is believed to be metabolically inert in most circumstances.