RT Journal Article
SR Electronic
T1 Successful Treatment of Hereditary Dominant Chorea With Carbamazepine
JF Pediatrics
JO Pediatrics
FD American Academy of Pediatrics
SP 1077
OP 1077
VO 83
IS 6
A1 ROULET, E.
A1 DEONNA, T.
YR 1989
UL http://pediatrics.aappublications.org/content/83/6/1077.1.abstract
AB Recently, Roig et al reported a significant improvement in five children with nonhereditary chorea of various origins by treating them with carbamazepine, 15 to 25 mg/kg. However, as discussed by these authors, the fluctuating and self-limited course of these disorders makes the efficacy of any drug difficult to demonstrate. Benign dominant hereditary chorea of early onset has a chronic course and, most adult patients, even welladjusted ones, have persistent motor impairment.