PT - JOURNAL ARTICLE AU - ROULET, E. AU - DEONNA, T. TI - Successful Treatment of Hereditary Dominant Chorea With Carbamazepine DP - 1989 Jun 01 TA - Pediatrics PG - 1077--1077 VI - 83 IP - 6 4099 - http://pediatrics.aappublications.org/content/83/6/1077.1.short 4100 - http://pediatrics.aappublications.org/content/83/6/1077.1.full SO - Pediatrics1989 Jun 01; 83 AB - Recently, Roig et al reported a significant improvement in five children with nonhereditary chorea of various origins by treating them with carbamazepine, 15 to 25 mg/kg. However, as discussed by these authors, the fluctuating and self-limited course of these disorders makes the efficacy of any drug difficult to demonstrate. Benign dominant hereditary chorea of early onset has a chronic course and, most adult patients, even welladjusted ones, have persistent motor impairment.