RT Journal Article
SR Electronic
T1 An X-Linked Recessive Cardiomyopathy with Abnormal Mitochondria
JF Pediatrics
JO Pediatrics
FD American Academy of Pediatrics
SP 24
OP 29
VO 64
IS 1
A1 Neustein, Harry B.
A1 Lurie, Paul R.
A1 Dahms, Beverly
A1 Takahashi, Masato
YR 1979
UL http://pediatrics.aappublications.org/content/64/1/24.abstract
AB A transvascular endomyocardial biopsy from an infant with cardiomyopathy and chronic congestive heart failure showed abnormal mitochondria when examined by electron microscopy. At necropsy, similar abnormal mitochondria were seen in skeletal muscles, liver, and kidney. The patient's family pedigree revealed several male babies who had cardiac disease and died in infancy. Myocardium obtained at necropsy from three cousins contained mitochondria with abnormalities similar to those from the proband. An X-linked recessive cardiomyopathy seems likely in this family.