PT  - JOURNAL ARTICLE
AU  - Pomerance, Herbert H.
AU  - Rader, Richard E.
TI  - Crystal Formation: A New Complication of Total Parenteral Nutrition
DP  - 1973 Dec 01
TA  - Pediatrics
PG  - 864--866
VI  - 52
IP  - 6
4099  - http://pediatrics.aappublications.org/content/52/6/864.short
4100  - http://pediatrics.aappublications.org/content/52/6/864.full
SO  - Pediatrics1973 Dec 01; 52
AB  - Since 1971, the Newborn Intensive Care Unit (NICU) of the Charleston Area Medical Center has developed considerable experience with Total Parenteral Nutrition (TPN). A new technical complication of this procedure has been encountered and is reported herewith. It is not the purpose of this communication to repeat the background of TPN,1 or to detail the case histories involved. Initially, like others, we used a mixture containing a casein hydrolysate (5% Amigen and 5% Dextrose Injection*), additional glucose, and minerals including calcium gluconate. In May 1972 we changed our formula to include a fibrin hydrolysate (Aminosol 5% in D5W†). At the same time, we added phosphate ion by changing from potassium chloride to potassium acid phosphate (Table I) .