PT  - JOURNAL ARTICLE
AU  - Feigin, Ralph D.
AU  - Middelkamp, J. Neal
AU  - Kissane, John M.
AU  - Warren, Richard J.
TI  - Agammaglobulinemia and Thymic Dysplasia Associated with Ectodermal Dysplasia
DP  - 1971 Jan 01
TA  - Pediatrics
PG  - 143--147
VI  - 47
IP  - 1
4099  - http://pediatrics.aappublications.org/content/47/1/143.short
4100  - http://pediatrics.aappublications.org/content/47/1/143.full
SO  - Pediatrics1971 Jan 01; 47
AB  - A 5-month-old female with agammaglobulinemia, thymic dysplasia, ectodermal dysplasia, and an erythematous icthyosiform dermatitis has been presented. Death at 7 months of age was the result of pneumocystis carinii pneumonia. The association of a broadly based immunologic deficit with ectodermal defects noted at birth lends support to the concept that a basic genetic abnormality may disturb the development of a number of mesenchymal components. It also suggests that skeletal anomalies are not invariably associated with the immunologic and ectodermal defects.