PT  - JOURNAL ARTICLE
AU  - CLEMENTS, JOHN A.
AU  - KLAUS, MARSHALL H.
AU  - TOOLEY, WILLIAM H.
TI  - Letters to the Editor
DP  - 1965 Sep 01
TA  - Pediatrics
PG  - 452--453
VI  - 36
IP  - 3
4099  - http://pediatrics.aappublications.org/content/36/3/452.short
4100  - http://pediatrics.aappublications.org/content/36/3/452.full
SO  - Pediatrics1965 Sep 01; 36
AB  - Dr. Ivanhoe suggests the interesting possibility that pulmonary venoconstriction may be an important feature of the idiopathic respiratory distress syndrome. While our physiological studies are consistent with pulmonary vascular obstruction on either the pre-or postcapillary side, there is evidence that the major obstruction is precapillary. The small pulmonary arterioles in lungs of infants dying with respiratory distress have thick walls and small lumina. When we perfused these lungs in vitro with blood or plasma, very low flows were observed unless pressures in excess of 200 cm of water were applied.