RT Journal Article
SR Electronic
T1 ESTIMATION OF THE SERUM BETA<sub>1C</sub> GLOBULIN CONCENTRATION: ITS RELATION TO THE SERUM HEMOLYTIC COMPLEMENT TITER
JF Pediatrics
JO Pediatrics
FD American Academy of Pediatrics
SP 765
OP 769
VO 35
IS 5
A1 Klemperer, Martin R.
A1 Gotoff, Samuel P.
A1 Alper, Chester A.
A1 Levin, Alan S.
A1 Rosen, Fred S.
YR 1965
UL http://pediatrics.aappublications.org/content/35/5/765.abstract
AB The depression of a single serum protein, the beta1C globulin (normally 130-155 mg/ 100 ml) to below 80 mg/100 ml is manifested by a decreased hemolytic complement titer. Since this protein can be measured by an immunodiffusion methol, its immunoassay can be used as a substitute for the hemolytic titration of complement in the diagnosis of patients with acute glomerulonephritis, systemic lupus erythematosus, and the nephrotic syndrome. A rapid immunoassay of the serum beta1C globulin can be easily performed.