PT  - JOURNAL ARTICLE
AU  - Broderick, Lori
AU  - Tremoulet, Adriana H.
AU  - Burns, Jane C.
AU  - Bastian, John F.
AU  - Hoffman, Hal M.
TI  - Recurrent Fever Syndromes in Patients After Recovery From Kawasaki Syndrome
AID  - 10.1542/peds.2010-1218
DP  - 2011 Feb 01
TA  - Pediatrics
PG  - e489--e493
VI  - 127
IP  - 2
4099  - http://pediatrics.aappublications.org/content/127/2/e489.short
4100  - http://pediatrics.aappublications.org/content/127/2/e489.full
SO  - Pediatrics2011 Feb 01; 127
AB  - The recurrence of fever in a child with a history of Kawasaki syndrome (KS) poses a dilemma for clinicians who must consider the possibility of recurrent KS. In this report we present the cases of 4 patients who presented with classical symptoms of KS, were successfully treated with intravenous immunoglobulin, and later experienced a reappearance of inflammatory symptoms in a pattern consistent with a recurrent fever syndrome. The association of these syndromes within the same patient suggests that some patients may have a genetic propensity toward altered immune responses and autoinflammatory syndromes. We propose that these 2 syndromes exist within a family of febrile disorders related to innate immune dysregulation.