RT Journal Article
SR Electronic
T1 Oral Bisphosphonate Therapy for Vitamin D Intoxication of the Infant
JF Pediatrics
JO Pediatrics
FD American Academy of Pediatrics
SP 899
OP 901
DO 10.1542/peds.111.4.899
VO 111
IS 4
A1 Bereket, Abdullah
A1 Erdogan, Tulay
YR 2003
UL http://pediatrics.aappublications.org/content/111/4/899.abstract
AB Vitamin D intoxication in infancy has serious consequences attributable to acute hypercalcemia and subsequent hypercalcuria/nephrocalcinosis. Current treatments of patients with vitamin D intoxication are unsatisfactory and associated with prolonged hypercalcemia. We now report the use of oral alendronate sodium in a 3-month-old infant with vitamin D intoxication. Short-term oral alendronate sodium treatment effectively corrected hypercalcemia/hypercalciuria, decreased the duration of hospitalization, and appears safe in 15 months of observation.