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American Academy of Pediatrics
Article

Introduction of Complementary Foods and the Relationship to Food Allergy

Kate E.C. Grimshaw, Joe Maskell, Erin M. Oliver, Ruth C.G. Morris, Keith D. Foote, E.N. Clare Mills, Graham Roberts and Barrie M. Margetts
Pediatrics November 2013, peds.2012-3692; DOI: https://doi.org/10.1542/peds.2012-3692
Kate E.C. Grimshaw
aClinical and Experimental Sciences Academic Unit and
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Joe Maskell
bPublic Health Sciences and Medical Statistics, University of Southampton, Southampton, United Kingdom;
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Erin M. Oliver
aClinical and Experimental Sciences Academic Unit and
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Ruth C.G. Morris
cWellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom;
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Keith D. Foote
dHampshire Hospitals Foundation Trust, Winchester, United Kingdom; and
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E.N. Clare Mills
eInstitute of Inflammation and Repair, Manchester Academic Health Science Centre, Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom
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Graham Roberts
aClinical and Experimental Sciences Academic Unit and
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Barrie M. Margetts
fPrimary Care and Population Sciences Academic Unit, University of Southampton Faculty of Medicine, Southampton, United Kingdom;
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Abstract

OBJECTIVES: To address questions regarding breastfeeding, complementary feeding, allergy development, and current infant-feeding recommendations.

METHODS: This was a nested, case-control within a cohort study in which mothers of 41 infants diagnosed with food allergy by the age of 2 years (according to double-blind, placebo-controlled food challenge) and their 82 age-matched controls kept prospective food diaries of how their infants were fed in the first year of life.

RESULTS: Infants who were diagnosed with food allergy by the time they were 2 years of age were introduced to solids earlier (≤16 weeks of age) and were less likely to be receiving breast milk when cow’s milk protein was first introduced into their diet.

CONCLUSIONS: This study supports the current American Academy of Pediatrics’ allergy prevention recommendations and the European Society of Pediatric Gastroenterology, Hepatology and Nutrition recommendations on complementary feeding to not introduce solids before 4 to 6 months of age. It also supports the American Academy of Pediatrics’ breastfeeding recommendations that breastfeeding should continue while solids are introduced into the diet and that breastfeeding should continue for 1 year, or longer, as mutually desired by mother and infant.

  • breastfeeding
  • food allergy
  • infant feeding
  • prevention
  • Abbreviations:
    DBPCFC —
    double-blind, placebo-controlled food challenge
    PIFA —
    Prevalence of Infant Food Allergy Study
    WHO —
    World Health Organization
    • Accepted September 13, 2013.
    • Copyright © 2013 by the American Academy of Pediatrics
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    Vol. 144, Issue 6
    1 Dec 2019
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    Introduction of Complementary Foods and the Relationship to Food Allergy
    Kate E.C. Grimshaw, Joe Maskell, Erin M. Oliver, Ruth C.G. Morris, Keith D. Foote, E.N. Clare Mills, Graham Roberts, Barrie M. Margetts
    Pediatrics Nov 2013, peds.2012-3692; DOI: 10.1542/peds.2012-3692

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    Introduction of Complementary Foods and the Relationship to Food Allergy
    Kate E.C. Grimshaw, Joe Maskell, Erin M. Oliver, Ruth C.G. Morris, Keith D. Foote, E.N. Clare Mills, Graham Roberts, Barrie M. Margetts
    Pediatrics Nov 2013, peds.2012-3692; DOI: 10.1542/peds.2012-3692
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