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American Academy of Pediatrics
Article

Measuring Adverse Events and Levels of Harm in Pediatric Inpatients With the Global Trigger Tool

Eric S. Kirkendall, Elizabeth Kloppenborg, James Papp, Denise White, Carol Frese, Deborah Hacker, Pamela J. Schoettker, Stephen Muething and Uma Kotagal
Pediatrics October 2012, peds.2012-0179; DOI: https://doi.org/10.1542/peds.2012-0179
Eric S. Kirkendall
aDivision of Hospital Medicine,
bJames M. Anderson Center for Health Systems Excellence, and
cDivision of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
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Elizabeth Kloppenborg
bJames M. Anderson Center for Health Systems Excellence, and
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James Papp
bJames M. Anderson Center for Health Systems Excellence, and
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Denise White
bJames M. Anderson Center for Health Systems Excellence, and
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Carol Frese
bJames M. Anderson Center for Health Systems Excellence, and
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Deborah Hacker
bJames M. Anderson Center for Health Systems Excellence, and
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Pamela J. Schoettker
bJames M. Anderson Center for Health Systems Excellence, and
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Stephen Muething
aDivision of Hospital Medicine,
bJames M. Anderson Center for Health Systems Excellence, and
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Uma Kotagal
bJames M. Anderson Center for Health Systems Excellence, and
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Abstract

OBJECTIVES: To evaluate and characterize the Global Trigger Tool’s (GTT's) utility in a pediatric population; to measure the rate of harm at our institution and compare it with previously established trigger tools and benchmark rates; and to describe the distribution of harm of the detected events.

METHODS: Per the GTT methodology, 240 random inpatient charts were retrospectively reviewed over a 12-month pilot period for the presence of 53 predefined safety triggers. When triggers were detected, the reviewers investigated the chart more thoroughly to decide whether an adverse event occurred. Agreement with a physician reviewer was then reached, and a level of harm was assigned.

RESULTS: A total of 404 triggers were detected (1.7 triggers per patient), and 88 adverse events were identified. Rates of 36.7 adverse events per 100 admissions and 76.3 adverse events per 1000 patient-days were calculated. Sixty-two patients (25.8%) had at least 1 adverse event during their hospitalization, and 18 (7.5%) had >1 event identified. Three-quarters of the events were category E (temporary harm). Two events required intervention to sustain life (category H). Two of the 6 trigger modules identified 95% of the adverse events.

CONCLUSIONS: The GTT demonstrated utility in the pediatric inpatient setting. With the use of the trigger tool, we identified a rate of harm 2 to 3 times higher than previously published pediatric rates. Modifications to the trigger tool to address pediatric-specific issues could increase the test characteristics of the tool.

  • global trigger tool
  • adverse events
  • patient safety
  • inpatient harm
  • medical errors
  • Abbreviations:
    ADE —
    adverse drug event
    AE —
    adverse event
    CCHMC —
    Cincinnati Children’s Hospital Medical Center
    CI —
    confidence interval
    GTT —
    global trigger tool
    IHI —
    Institute for Healthcare Improvement
    NCC MERP —
    National Coordinating Council for Medication Error Reporting and Prevention
    • Accepted July 2, 2012.
    • Copyright © 2012 by the American Academy of Pediatrics

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    1 Apr 2021
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    Measuring Adverse Events and Levels of Harm in Pediatric Inpatients With the Global Trigger Tool
    Eric S. Kirkendall, Elizabeth Kloppenborg, James Papp, Denise White, Carol Frese, Deborah Hacker, Pamela J. Schoettker, Stephen Muething, Uma Kotagal
    Pediatrics Oct 2012, peds.2012-0179; DOI: 10.1542/peds.2012-0179

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    Measuring Adverse Events and Levels of Harm in Pediatric Inpatients With the Global Trigger Tool
    Eric S. Kirkendall, Elizabeth Kloppenborg, James Papp, Denise White, Carol Frese, Deborah Hacker, Pamela J. Schoettker, Stephen Muething, Uma Kotagal
    Pediatrics Oct 2012, peds.2012-0179; DOI: 10.1542/peds.2012-0179
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