Abstract
The ability of activated T cells to adhere to ASM and to further induce DNA synthesis in growth-arrested cells may have important implications for smooth muscle in the asthmatic lung. Perhaps the smooth muscle cell itself plays a role in the inflammation of asthma. In addition, an activated T cell population in the lungs which stimulates ASM to produce DNA could possibly lead to hypertrophy of this cell type.
- Copyright © 1995 by the American Academy of Pediatrics
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T LYMPHOCYTES ADHERE TO AIRWAY SMOOTH MUSCLE CELLS VIA INTEGRINS AND CD-44, AND INDUCE SMOOTH MUSCLE CELL DNA SYNTHESIS
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