Fetal alcohol syndrome (FAS) was first recognized as a distinct clinical entity by Jones and Smith in 1973.1 In their first reports,2,3 all affected children had been born to severely alcoholic women, and had in common problems in three major categories:
1. prenatal and/or postnatal growth deficiency;
2. abnormal brain function reflected in mental deficit; and
3. a distinctive pattern of mild facial dysmorphology.
Later psychological studies revealed a pattern of behavioral aberration, which is quite common in affected children, but has not been shown to be unique to FAS.4,5
As is usually the case with newly described clinical syndromes, diagnosticians soon began to realize that they were encountering children with some, but not all the classical signs of FAS.
- Received February 4, 1994.
- Accepted July 8, 1994.
- Copyright © 1995 by the American Academy of Pediatrics