Abstract
We appreciate Dr Philip's sharing his experience on the use of serial C-reactive protein (CRP) for monitoring neonates with sepsis or pneumonia due to group B streptococcus. In his letter, Dr Philip alluded to the use of normal serial CRP within 24 to 48 hours of life as a guide to discontinuing antibiotic therapy when cultures are negative. Our current practice is carried further. Based on our published data and our continuing experience, we discontinue antibiotic therapy in asymptomatic infants, even in those with positive blood cultures.
- Copyright © 1994 by the American Academy of Pediatrics
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