Abstract
Severe hyperglycemia without ketosis at the clinical onset of insulin-dependent diabetes mellitus (IDDM) has been reported in children and adolescents.1 Non-diabetic children can develop modest hyperglycemia (usually in the range of 11 to 14 mmol/L (200 to 250 mg/dL)) without ketosis in response to physiologic stress such as trauma, burns, or sepsis,2,3 but severe hyperglycemia is seen rarely in this setting. We recently encountered the case of a 22-month-old infant with severe nonketotic hyperglycemic hyperosmolar syndrome due to gastroenteritis and dehydration who rapidly recovered and has had no subsequent evidence of diabetes mellitus.
CASE REPORT
A 22-month-old Hispanic male infant was brought to the Yale-New Haven Hospital Pediatric Emergency Room with a 48-hour history of fever, diarrhea (8 to 10 stools/day), and vomiting (approximately hourly for the previous 24 hours).
- Received January 11, 1991.
- Accepted February 21, 1991.
- Copyright © 1992 by the American Academy of Pediatrics
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