Abstract
1954: "All premature infants were alternately placed in a group to be [gradually] weaned from oxygen (Group A) and a group to be suddenly withdrawn from oxygen (Group B)....
If an infant was thought to be developing the disease [progressive RLF] the infant was placed back in oxygen at the same concentration from which he had been removed. Because our results with oxygen therapy had been uniformly successful, we did not feel it was fair to withhold treatment in order to obtain control cases."2
1981: "We undertook a double-blind clinical study to determine the efficacy of vitamin E in preventing the development of severe retrolental fibroplasia.... Any infant found to have Grade III was removed form the study and treated surgically."3
1981: "In this center, surgical intervention with cryotherapy and scleral buckling procedures have produced favorable responses in RLF cases."4
- Copyright © 1982 by the American Academy of Pediatrics
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