Abstract
Idiopathic growth hormone deficiency is unusual in twin sibships. We report three twins with growth hormone deficiency whose co-twins are growing normally and have no evidence of hypothalamicpituitary dysfunction. It is likely that the affected children sustained perinatal insult. The data illustrate that idiopathic growth hormone deficiency should be considered in the differential diagnosis when there is a major discrepancy in height between twins.
CASE REPORTS
Case 1
Male twins I were born at 36 weeks' gestation to a 27-year-old gravida 3, para 2. There was no history of abnormal vaginal bleeding, infection or, toxemia. Labor was spontaneous and lasted two hours.
- Copyright © 1982 by the American Academy of Pediatrics
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