Skip to main content

Advertising Disclaimer »

Main menu

  • Journals
    • Pediatrics
    • Hospital Pediatrics
    • Pediatrics in Review
    • NeoReviews
    • AAP Grand Rounds
    • AAP News
  • Authors/Reviewers
    • Submit Manuscript
    • Author Guidelines
    • Reviewer Guidelines
    • Open Access
    • Editorial Policies
  • Content
    • Current Issue
    • Online First
    • Archive
    • Blogs
    • Topic/Program Collections
    • AAP Meeting Abstracts
  • Pediatric Collections
    • COVID-19
    • Racism and Its Effects on Pediatric Health
    • More Collections...
  • AAP Policy
  • Supplements
  • Multimedia
    • Video Abstracts
    • Pediatrics On Call Podcast
  • Subscribe
  • Alerts
  • Careers
  • Other Publications
    • American Academy of Pediatrics

User menu

  • Log in

Search

  • Advanced search
American Academy of Pediatrics

AAP Gateway

Advanced Search

AAP Logo

  • Log in
  • Journals
    • Pediatrics
    • Hospital Pediatrics
    • Pediatrics in Review
    • NeoReviews
    • AAP Grand Rounds
    • AAP News
  • Authors/Reviewers
    • Submit Manuscript
    • Author Guidelines
    • Reviewer Guidelines
    • Open Access
    • Editorial Policies
  • Content
    • Current Issue
    • Online First
    • Archive
    • Blogs
    • Topic/Program Collections
    • AAP Meeting Abstracts
  • Pediatric Collections
    • COVID-19
    • Racism and Its Effects on Pediatric Health
    • More Collections...
  • AAP Policy
  • Supplements
  • Multimedia
    • Video Abstracts
    • Pediatrics On Call Podcast
  • Subscribe
  • Alerts
  • Careers

Discover Pediatric Collections on COVID-19 and Racism and Its Effects on Pediatric Health

American Academy of Pediatrics
Article

Effects of Inspired Oxygen on Echocardiographic Assessment of Pulmonary Vascular Resistance and Myocardial Contractility in Bronchopulmonary Dysplasia

Henry L. Halliday, Fe M. Dumpit and June P. Brady
Pediatrics March 1980, 65 (3) 536-540;
Henry L. Halliday
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fe M. Dumpit
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
June P. Brady
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • Comments
Loading
Download PDF

Abstract

We studied the effects of minor changes of inspired oxygen in ten preterm infants (birth weight: 700 to 1,780 gm; postnatal age: 4 to 18 weeks) with severe bronchopulmonary dysplasia. We compared the echocardiogram, capillary blood gases, and calculated venous admixture when the oxygen level was raised or lowered by 10% of the initial value. Mean ambient inspired oxygen was 0.31, capillary Po2 was 62 torr, and calculated venous admixture was 40%. The ratio of right ventricular preejection period to right ventricular ejection time (RPEP/RVET) was 0.32, suggesting mild increase in pulmonary vascular resistance. In all instances, there was echocar-diographic evidence of further increase in pulmonary vascular resistance with a minor decrease in inspired oxygen. Lowering the inspired oxygen to 0.28 resulted in a reduction in Pao2 to 54 torr, an increase in calculated venous admixture to 47%, and an increase in RPEP/RVET to 0.36 (P <.001). Raising the inspired oxygen to 0.34 increased Pao2 to 72 torr but had no effect on RPEP/RVET. Calculated venous admixture decreased to 33% (P <.001). Myocardial contractility did not change with decrease in inspired oxygen but improved slightly with increase in inspired oxygen. These preliminary findings suggest that in infants with bronchopulmonary dysplasia the Pao2 should be kept > 55 torr and the RPEP/RVET < 0.35 to avoid the development of right heart failure.

  • Received April 2, 1979.
  • Accepted June 20, 1979.
  • Copyright © 1980 by the American Academy of Pediatrics

Individual Login

Log in
You will be redirected to aap.org to login or to create your account.

Institutional Login

via Institution

You may be able to gain access using your login credentials for your institution. Contact your librarian or administrator if you do not have a username and password.

Log in through your institution

If your organization uses OpenAthens, you can log in using your OpenAthens username and password. To check if your institution is supported, please see this list. Contact your library for more details.

Pay Per Article - You may access this article (from the computer you are currently using) for 2 days for US$25.00

Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.

Offer Reprints

PreviousNext
Back to top

Advertising Disclaimer »

In this issue

Pediatrics
Vol. 65, Issue 3
1 Mar 1980
  • Table of Contents
  • Index by author
PreviousNext
Email Article

Thank you for your interest in spreading the word on American Academy of Pediatrics.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Effects of Inspired Oxygen on Echocardiographic Assessment of Pulmonary Vascular Resistance and Myocardial Contractility in Bronchopulmonary Dysplasia
(Your Name) has sent you a message from American Academy of Pediatrics
(Your Name) thought you would like to see the American Academy of Pediatrics web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Request Permissions
Article Alerts
Log in
You will be redirected to aap.org to login or to create your account.
Or Sign In to Email Alerts with your Email Address
Citation Tools
Effects of Inspired Oxygen on Echocardiographic Assessment of Pulmonary Vascular Resistance and Myocardial Contractility in Bronchopulmonary Dysplasia
Henry L. Halliday, Fe M. Dumpit, June P. Brady
Pediatrics Mar 1980, 65 (3) 536-540;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Effects of Inspired Oxygen on Echocardiographic Assessment of Pulmonary Vascular Resistance and Myocardial Contractility in Bronchopulmonary Dysplasia
Henry L. Halliday, Fe M. Dumpit, June P. Brady
Pediatrics Mar 1980, 65 (3) 536-540;
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Download PDF
Insight Alerts
  • Table of Contents

Jump to section

  • Article
  • Info & Metrics
  • Comments

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Automated Closed Loop Control of Inspired Oxygen Concentration
  • Prospective Analysis of Pulmonary Hypertension in Extremely Low Birth Weight Infants
  • BTS guidelines for home oxygen in children
  • Hospital Discharge of the High-Risk Neonate
  • Does the monitoring method influence stability of oxygenation in preterm infants? A randomised crossover study of saturation versus transcutaneous monitoring
  • Monitoring cardiovascular function in infants with chronic lung disease of prematurity
  • Is Oxygen More Toxic Than Currently Believed?
  • Closed-Loop Controlled Inspired Oxygen Concentration for Mechanically Ventilated Very Low Birth Weight Infants With Frequent Episodes of Hypoxemia
  • Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestation
  • Haemodynamic effects of altering arterial oxygen saturation in preterm infants with respiratory failure
  • Hospital Discharge of the High-Risk Neonate--Proposed Guidelines
  • Google Scholar

More in this TOC Section

  • Appendectomy Versus Observation for Appendicitis in Neutropenic Children With Cancer
  • The Revised WIC Food Package and Child Development: A Quasi-Experimental Study
  • Nurse Home Visiting and Maternal Mental Health: 3-Year Follow-Up of a Randomized Trial
Show more Articles

Similar Articles

  • Journal Info
  • Editorial Board
  • Editorial Policies
  • Overview
  • Licensing Information
  • Authors/Reviewers
  • Author Guidelines
  • Submit My Manuscript
  • Open Access
  • Reviewer Guidelines
  • Librarians
  • Institutional Subscriptions
  • Usage Stats
  • Support
  • Contact Us
  • Subscribe
  • Resources
  • Media Kit
  • About
  • International Access
  • Terms of Use
  • Privacy Statement
  • FAQ
  • AAP.org
  • shopAAP
  • Follow American Academy of Pediatrics on Instagram
  • Visit American Academy of Pediatrics on Facebook
  • Follow American Academy of Pediatrics on Twitter
  • Follow American Academy of Pediatrics on Youtube
  • RSS
American Academy of Pediatrics

© 2021 American Academy of Pediatrics