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American Academy of Pediatrics
Article

A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine

G. J. Schwartz, G. B. Haycock, C. M. Edelmann and Adrian Spitzer
Pediatrics August 1976, 58 (2) 259-263;
G. J. Schwartz
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G. B. Haycock
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C. M. Edelmann Jr.
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Adrian Spitzer
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Abstract

Based on statistical analysis of data in 186 children, a formula was derived which allows accurate estimation of glomerular filtration rate (GFR) from plasma creatinine and body length (GFR (ml/min/1.73 sq m) = 0.55 length (cm)/Pcr (mg/dl). Its application to clearance data in a separate group of 223 children reveals excellent agreement with GFR estimated by the Ccr (r = .935) or Cin (r = .905). This formula should be useful for adjusting dosages of drugs excreted by the kidney and detecting significant changes in renal function.

  • Received March 18, 1975.
  • Accepted August 30, 1975.
  • Copyright © 1976 by the American Academy of Pediatrics
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Pediatrics
Vol. 58, Issue 2
1 Aug 1976
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A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine
G. J. Schwartz, G. B. Haycock, C. M. Edelmann, Adrian Spitzer
Pediatrics Aug 1976, 58 (2) 259-263;

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A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine
G. J. Schwartz, G. B. Haycock, C. M. Edelmann, Adrian Spitzer
Pediatrics Aug 1976, 58 (2) 259-263;
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