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American Academy of Pediatrics
Article

Neutrophil and Band Counts in the Diagnosis of Neonatal Infections

Gregory I. Akenzua, Yin T. Hui, Ruth Milner and Alvin Zipursky
Pediatrics July 1974, 54 (1) 38-42;
Gregory I. Akenzua
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Yin T. Hui
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Ruth Milner
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Alvin Zipursky
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Abstract

A system has been developed for the evaluation of hematological data in the newborn. Normal values were established for segmented (neutrophil) and nonsegmented (band) polymorphonuclear leukocytes in the peripheral blood of 169 healthy full-term infants during the first five days of life. This normal data is displayed graphically and the values for infants under study are compared directly.

Newborn infants with proven bacterial infections had normal neutrophil counts; however, the band counts increased significantly beyond the normal range. Therefore, the simple laboratory procedure for ennumerating band neutrophils with comparison of absolute values and changes to a normal range represents a hematologic technique of major importance in the diagnosis of sepsis of the newborn infant.

  • Received September 27, 1973.
  • Accepted January 31, 1974.
  • Copyright © 1974 by the American Academy of Pediatrics

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Pediatrics
Vol. 54, Issue 1
1 Jul 1974
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Neutrophil and Band Counts in the Diagnosis of Neonatal Infections
Gregory I. Akenzua, Yin T. Hui, Ruth Milner, Alvin Zipursky
Pediatrics Jul 1974, 54 (1) 38-42;

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Neutrophil and Band Counts in the Diagnosis of Neonatal Infections
Gregory I. Akenzua, Yin T. Hui, Ruth Milner, Alvin Zipursky
Pediatrics Jul 1974, 54 (1) 38-42;
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  • A Randomized Trial of Granulocyte-Macrophage Colony-Stimulating Factor in Neonates With Sepsis and Neutropenia
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  • Reduction of Unnecessary Antibiotic Therapy in Newborn Infants Using Interleukin-8 and C-Reactive Protein as Markers of Bacterial Infections
  • The Neonatal "Sepsis Work-up": Personal Reflections on the Development of an Evidence-Based Approach Toward Newborn Infections in a Managed Care Organization
  • Circulating Neutrophils in Septic Preterm Neonates: Comparison of Two Reference Ranges
  • C-Reactive Protein Is a Useful Marker for Guiding Duration of Antibiotic Therapy in Suspected Neonatal Bacterial Infection
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