During the winter and spring of 1970 to 1971, an epidemic of measles occurred in the St. Louis area. During a study of this epidemic, 12 children had clinical illnesses suggesting the "atypical measles" syndrome, but six of these children had received only live attenauted measles vaccines. The illnesses in these six children were qualitatively similar to those in the six children who had been immunized with killed measles vaccines, but they were quantitatively less severe. Acute-phase measles HAI antibody titers in the recipients of live vaccines were greater than those of killed vaccine recipients, whereas the converse was true of the convalescent-phase serum titers.
- Received March 20, 1972.
- Accepted July 3, 1972.
- Copyright © 1972 by the American Academy of Pediatrics