Abstract
Twenty children who had previously received mumps vaccine developed parotid swelling which was diagnosed as mumps 3 to 39 months following inoculation. In only eight of seventeen children who were studied serologically could the diagnosis of mumps be confirmed. Since these children were immunized over a 4-year period in four different pediatric offices, it is not likely that a particular lot of vaccine or immunizing procedure was at fault. These eight children probably represent vaccine failure. Serologic, virus isolation, clinical or epidemiologic studies failed to reveal the cause of parotid swelling in the remaining children.
It is apparent that children who develop parotid swelling following immunization with mumps vaccine cannot be assumed to have mumps. Serologic studies are required to identify the vaccine failures.
- Received July 14, 1971.
- Accepted March 17, 1972.
- Copyright © 1972 by the American Academy of Pediatrics
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