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Discover Pediatric Collections on COVID-19 and Racism and Its Effects on Pediatric Health

American Academy of Pediatrics
Article

NOSOCOMIAL INFECTIONS DUE TO KANAMYCIN-RESISTANT, [R]-FACTOR CARRYING ENTERIC ORGANISMS IN AN INTENSIVE CARE NURSERY

Kathleen Davis Eisenach, Rose Marie Reber, Donald V. Eitzman and Herman Baer
Pediatrics September 1972, 50 (3) 395-402;
Kathleen Davis Eisenach
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Rose Marie Reber
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Donald V. Eitzman
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Herman Baer
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Abstract

During a 12-month period, an infection rate of 10% with kanamycin-resistant, resistance-factor (R-factor) carrying enteric organisms was observed in 236 infants admitted to an intensive care nursery (ICN), with a mortality of 38%. Maternal and perinatal complications did not predispose to infection. In contrast, a combination of therapeutic procedures (surgery, use of penicillin and kanamycin, catheters, ventilation) was associated with increased risk of infection.

About 90% of the infants admitted to the ICN became colonized with the resistant organisms, and intestinal tract and groin showed the highest rate of colonization. The majority of the personnel in the ICN carried the organisms in the intestinal tract and on the hands. Handwashing with hexachlorophene failed to reduce the contamination significantly. While the main source of organisms was the colonized and/or infected infants, transmission probably occurred via the hands of personnel.

  • Received August 27, 1971.
  • Accepted February 7, 1972.
  • Copyright © 1972 by the American Academy of Pediatrics

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Pediatrics
Vol. 50, Issue 3
1 Sep 1972
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NOSOCOMIAL INFECTIONS DUE TO KANAMYCIN-RESISTANT, [R]-FACTOR CARRYING ENTERIC ORGANISMS IN AN INTENSIVE CARE NURSERY
Kathleen Davis Eisenach, Rose Marie Reber, Donald V. Eitzman, Herman Baer
Pediatrics Sep 1972, 50 (3) 395-402;

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NOSOCOMIAL INFECTIONS DUE TO KANAMYCIN-RESISTANT, [R]-FACTOR CARRYING ENTERIC ORGANISMS IN AN INTENSIVE CARE NURSERY
Kathleen Davis Eisenach, Rose Marie Reber, Donald V. Eitzman, Herman Baer
Pediatrics Sep 1972, 50 (3) 395-402;
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