Abstract
The depression of a single serum protein, the beta1C globulin (normally 130-155 mg/ 100 ml) to below 80 mg/100 ml is manifested by a decreased hemolytic complement titer. Since this protein can be measured by an immunodiffusion methol, its immunoassay can be used as a substitute for the hemolytic titration of complement in the diagnosis of patients with acute glomerulonephritis, systemic lupus erythematosus, and the nephrotic syndrome. A rapid immunoassay of the serum beta1C globulin can be easily performed.
- Received July 6, 1964.
- Accepted January 6, 1965.
- Copyright © 1965 by the American Academy of Pediatrics
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ESTIMATION OF THE SERUM BETA1C GLOBULIN CONCENTRATION: ITS RELATION TO THE SERUM HEMOLYTIC COMPLEMENT TITER
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