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Discover Pediatric Collections on COVID-19 and Racism and Its Effects on Pediatric Health

American Academy of Pediatrics
Research Briefs

Pediatric COVID-19 Cases Prelockdown and Postlockdown in Italy

Stefania Bellino, Maria Cristina Rota, Flavia Riccardo, Xanthi Andrianou, Alberto Mateo Urdiales, Martina Del Manso, Ornella Punzo, Antonino Bella, Alberto Villani, Patrizio Pezzotti and COVID-19 Working Group
Pediatrics February 2021, 147 (2) e2020035238; DOI: https://doi.org/10.1542/peds.2020-035238
Stefania Bellino
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
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Maria Cristina Rota
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
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Flavia Riccardo
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
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Xanthi Andrianou
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
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Alberto Mateo Urdiales
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
cEuropean Centre for Disease Prevention and Control, European Programme for Intervention Epidemiology Training, Stockholm, Sweden
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Martina Del Manso
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
cEuropean Centre for Disease Prevention and Control, European Programme for Intervention Epidemiology Training, Stockholm, Sweden
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Ornella Punzo
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
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Antonino Bella
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
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Alberto Villani
bPediatric Emergency Department and General Pediatrics, Children Hospital Bambino Gesù, Rome, Italy; and
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Patrizio Pezzotti
aDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy;
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    FIGURE 1

    Epidemic curve by date of positive test result and disease severity (asymptomatic or symptomatic) of COVID-19 cases patients <18 years of age in Italy, from February 23 to September 13, 2020. A, 0–1 year. B, 2–6 years. C, 7–12 years. D, 13–17 years. Asymptomatic is shown in light blue, and symptomatic is shown in red.

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    TABLE 1

    Risk Factors for Study Period (May 4 to September 13 versus February 23 to May 3, 2020) in Individuals <18 Years of Age in Italy; Multivariable Logistic Regression Model

    Risk FactorsFebruary 23 to May 3, %May 4 to September 13, %Study Period
    OR95% CIP
    Sex
     Boys48.548.8Reference——
     Girls,51.551.21.040.95–1.15.44
    Class of age, y
     0–113.29.7Reference——
     2–617.021.01.211.01–1.45.038
     7–1229.728.00.930.78–1.09.36
     13–1740.141.31.120.95–1.31.16
    Underling medical conditions
     No94.897.2Reference——
     Yes5.22.80.580.46–0.74<.001
    Disease severity
     Asymptomatic35.571.2Reference——
     Paucisymptomatic18.28.40.220.19–0.25<.001
     Mild40.318.50.200.18–0.22<.001
     Severe or critical6.01.90.110.09–0.15<.001
    Geographic area
     Northwest27.133.4Reference——
     Northeast34.030.80.600.53–0.68<.001
     Center18.316.60.760.66–0.89<.001
     South and Islands20.519.30.420.36–0.49<.001
    • February 23 to May 3: N = 3650; May 4 to September 13: N = 6197. CI, confidence interval; OR, odds ratio; —, not applicable.

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1 Feb 2021
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Pediatric COVID-19 Cases Prelockdown and Postlockdown in Italy
Stefania Bellino, Maria Cristina Rota, Flavia Riccardo, Xanthi Andrianou, Alberto Mateo Urdiales, Martina Del Manso, Ornella Punzo, Antonino Bella, Alberto Villani, Patrizio Pezzotti, COVID-19 Working Group
Pediatrics Feb 2021, 147 (2) e2020035238; DOI: 10.1542/peds.2020-035238

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Pediatric COVID-19 Cases Prelockdown and Postlockdown in Italy
Stefania Bellino, Maria Cristina Rota, Flavia Riccardo, Xanthi Andrianou, Alberto Mateo Urdiales, Martina Del Manso, Ornella Punzo, Antonino Bella, Alberto Villani, Patrizio Pezzotti, COVID-19 Working Group
Pediatrics Feb 2021, 147 (2) e2020035238; DOI: 10.1542/peds.2020-035238
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