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Discover Pediatric Collections on COVID-19 and Racism and Its Effects on Pediatric Health

American Academy of Pediatrics
Article

COVID-19 Transmission in US Child Care Programs

Walter S. Gilliam, Amyn A. Malik, Mehr Shafiq, Madeline Klotz, Chin Reyes, John Eric Humphries, Thomas Murray, Jad A. Elharake, David Wilkinson and Saad B. Omer
Pediatrics January 2021, 147 (1) e2020031971; DOI: https://doi.org/10.1542/peds.2020-031971
Walter S. Gilliam
aYale Child Study Center and
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Amyn A. Malik
cSchool of Medicine,
bYale Institute for Global Health,
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Mehr Shafiq
bYale Institute for Global Health,
dMailman School of Public Health, Columbia University, New York, New York; and
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Madeline Klotz
aYale Child Study Center and
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Chin Reyes
aYale Child Study Center and
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John Eric Humphries
eDepartment of Economics, Yale University, New Haven, Connecticut;
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Thomas Murray
fDepartment of Pediatrics,
gYale New Haven Children’s Hospital, New Haven, Connecticut
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Jad A. Elharake
bYale Institute for Global Health,
hSchools of Public Health and
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David Wilkinson
aYale Child Study Center and
iTobin Center for Economic Policy, and
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Saad B. Omer
bYale Institute for Global Health,
cSchool of Medicine,
hSchools of Public Health and
jNursing,
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Article Figures & Data

Tables

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    TABLE 1

    Descriptive Statistics for All Variables for Cases, Noncases in the Logistic Regression Analysis, and Matched Controls in the Case-Control Analysis

    Cases (n = 427)Noncases (n = 56 908)Matched Controls (n = 21 350)
    Exposure, %
     No52.249.151.9
     Yes47.850.948.1
    Race and/or ethnicity, %a
     American Indian or Alaskan native4.61.92.0
     Asian American2.13.53.7
     African American or Black23.414.714.8
     Native Hawaiian or other Pacific Islander0.90.50.5
     White54.372.171.7
     Prefer to not answer (race)18.79.69.6
     Hispanic, Latinx, or Spanish origin34.218.618.2
     Prefer to not answer (ethnicity)2.82.12.1
    Gender, %
     Female96.097.097.0
     Male3.32.32.3
     Nonbinary0.00.20.2
     Prefer to not answer0.70.50.5
    Age, y, mean (SD)45.71 (12.49)45.97 (12.30)46.19 (12.31)
    Child care type, %
     Center basedb65.871.472.2
     Family based or home based34.228.627.8
    Director or owner of center-based care, %
     No78.773.474.2
     Yes21.326.625.8
    Personal COVID-19 health precautions, mean (SD)
     Masks, hand-washing, and/or distancing, 0–32.86 (0.40)2.77 (0.52)2.80 (0.49)
     Avoiding social interactions, 0–32.34 (0.89)2.11 (1.04)2.13 (1.03)
     Avoiding high-risk situations and travel, 0–42.64 (0.74)2.71 (0.67)2.71 (0.66)
    County COVID-19 cumulative death rate, %c
     Low (0–0.0561 deaths per 1000)24.633.631.2
     Moderate (0.0564–0.2180 deaths per 1000)24.134.233.0
     High (0.2184–13.5248 deaths per 1000)51.332.335.8
    County household median income, %c
     Low ($13 242–$54 976)27.633.632.4
     Moderate ($54 979–$65 010)36.332.333.8
     High ($65 027–$136 268)36.134.233.8
    • ↵a Race and/or ethnicity options were “check all that apply”; resulting proportions may not add to 100%.

    • ↵b Center-based child care included (1) for-profit centers (32.5%), (2) nonprofit centers (27.4%), (3) school-based centers (16.7%), (4) Head Start centers (13.9%), (5) drop-in centers (2.0%), and (6) other centers (7.4%).

    • ↵c County-level data were trichotomized into proportionally equal thirds.

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    TABLE 2

    Infection-Control Efforts Reported in Open Child Care Programs During April 2020 (N = 20 550)

    Reporting Each Effort Every Day, %
    Once DailyTwice DailyThrice Daily
    Screening
     Child symptom screening78.440.7—
     Child temperature checks76.133.3—
     Staff symptom screening73.935.4—
     Staff temperature checks69.328.3—
    Disinfecting
     All indoor surfaces90.273.956.5
     All doorknobs, bathroom fixtures, handles90.371.154.3
     All toys, books, classroom materials81.755.239.6
     No child-accessible items that are hard to disinfect75.0——
    Hand hygiene
     All children washed hands frequently92.7——
     All staff washed hands frequently90.2——
    Masks and personal protective equipment
     All children (≥2 y old) wore facial masks11.8——
     All adults wore facial masks35.2——
     All adults wore aprons and/or changed clothes before work61.7——
     All adults wore gloves when handling children33.2——
    Cohorting
     No mixing of children between child groups53.6——
     No sharing of items between child groups67.3——
    Social distancing
     Seating or cots ≥6 ft apart68.0——
     Staggered arrival and departure times51.2——
     All children curbside drop-off and/or pickup78.8——
     All child belongings separated85.8——
     No eating family style or sharing food49.4——
    • Percentages indicate the proportion of providers reporting that a specific infection-control effort was employed either every day or (for some efforts) twice or thrice daily. —, not applicable.

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    TABLE 3

    Personal COVID-19 Health Precautions: Principal Component Analysis With Factor Loadings

    Factor 1Factor 2Factor 3
    Items
     Asked family and friends not to visit0.79——
     Avoided extended family and friends even if not symptomatic0.77——
     Avoided eating outside of home0.55——
     Avoided close contact with people who were sick—0.79—
     Avoided traveling to high COVID-19–infection places—0.71—
     Avoided social events they would normally attend—0.52—
     Canceled business trips, social trips, vacations—0.47—
     Tried to maintain at least 6 ft from others when outside home——0.75
     Wore facial covering or mask almost always when outside home——0.60
     Frequently washed or sanitized hands when outside home——0.57
    Factor statistics
     Eigen value3.361.060.99
     % variance accounted (from rotated sums of squared loadings)22.018.813.4
     Cronbach’s α0.750.860.82
    • Factor loadings are from Kaiser-normalized varimax rotation, suppressing <0.45. —, not applicable.

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    TABLE 4

    Comparison of Total Analytic Sample Versus National Estimates of Child Care Provider Demographics and County-Level Descriptions

    Total Analytic SampleNational Estimates
    Age, mean, y45.9738.70
    Men, %2.36.5
    Race and/or ethnicity, %
     American Indian or Alaskan native2.00.8
     Asian American3.53.9
     African American or Black14.715.1
     White72.069.9
     Hispanic18.722.0
    County COVID-19 deaths per 1000, mean0.340.30
    County household median income, mean $64 36263 179
    • Age, gender, and race and/or ethnicity comparisons are between the total analytic sample (N = 57 335) and national child care provider estimates based on the 2018 American Community Survey (ACS). ACS data are weighted national averages for individuals with an occupation of child care workers (occupation code 4600) between the ages of 18 and 65. For the ACS, Asian American includes Chinese, Japanese, and other Asian or Pacific Islander; Hispanic includes Mexican, Puerto Rican, Cuban, or other. County COVID-19 deaths per 1000 are the mean deaths per 1000 individuals for the counties of survey respondents versus the US national average. County household median income for survey respondents is the mean of the median annual household income of the counties of the survey respondents constructed by using the 2018 5-year ACS data. County household median income for the national child care provider estimate is the mean median income for the county in 2018 reported by the US Census.

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    TABLE 5

    Percentage of Children by Age Served by Respondents Open During the Pandemic

    All ProvidersCenter-Based ProvidersHome-Based Providers
    Infants (<1 y)8.38.28.3
    Toddlers (1–2 y)29.730.629.4
    Preschool-aged children (3–5 y)43.150.540.0
    School-aged children (≥6 y)18.910.822.3
    • View popup
    TABLE 6

    Adjusted Logistic Regression Unmatched Analysis Predicting Cases (n = 427) Versus Noncases (n = 56 908)

    OR95% Wald CIP
    Exposure to child care
     NoReferenceReferenceReference
     Yes1.060.82–1.38.66
    Race and/or ethnicity
     WhiteReferenceReferenceReference
     American Indian or Alaskan native2.371.46–3.86.001
     Asian American0.830.42–1.64.60
     African American or Black1.971.53–2.53<.001
     Native Hawaiian or other Pacific Islander1.860.65–5.29.25
     Prefer not to answer (race)1.591.17–2.16.003
     Hispanic2.131.63–2.77<.001
     Prefer not to answer (ethnicity)1.310.69–2.50.41
    Gendera
     FemaleReferenceReferenceReference
     Male1.600.93–2.75.09
     Prefer not to answer0.970.29–3.23.98
    Age1.000.99–1.01.78
    Child care type
     Center basedReferenceReferenceReference
     Family based or home based1.250.87–1.80.22
    Director or owner (of center-based care)
     NoReferenceReferenceReference
     Yes0.950.72–1.25.73
    Personal COVID-19 health precautions
     Masks, hand-washing, and/or distancing1.160.90–1.50.24
     Avoiding social interactions1.271.13–1.44.001
     Avoiding high-risk situations and travel0.720.62–0.84<.001
    County COVID-19 cumulative deaths
     LowReferenceReferenceReference
     Moderate1.130.83–1.54.45
     High1.601.19–2.15.002
    County median household income
     LowReferenceReferenceReference
     Moderate1.260.96–1.65.10
     High1.030.76–1.41.84
    Interaction effects
     Exposure × child care type0.850.54–1.34.49
    • The state where the child care program was located (all 50 states, plus the District of Columbia and Puerto Rico) was entered in the logistic regression analysis but is not reflected in the table.

    • ↵a No survey respondents self-identified as nonbinary, so we dropped this value from analysis.

    • View popup
    TABLE 7

    Adjusted Case-Controlled Conditional Logistic Regression Analysis Predicting Cases (n = 427) Versus Matched Controls (n = 21 350)

    OR95% CIP
    Exposure to child care0.940.73–1.21.64
    Child care type (family or home based)1.591.14–2.23<.01
    Interaction (child care type × exposure)0.820.53–1.26.37
    • Cases were propensity score–matched to controls by using 1:50 random matching without replacement with a caliper width of 0.2 × SD of the logit function. Values used in the propensity score included age, race, ethnicity, sex, director status, county-level COVID-19 death rate, county-level median household income, personal COVID-19 health precaution measures (3 continuous variables), and state where child care program was located (indicator variables).

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COVID-19 Transmission in US Child Care Programs
Walter S. Gilliam, Amyn A. Malik, Mehr Shafiq, Madeline Klotz, Chin Reyes, John Eric Humphries, Thomas Murray, Jad A. Elharake, David Wilkinson, Saad B. Omer
Pediatrics Jan 2021, 147 (1) e2020031971; DOI: 10.1542/peds.2020-031971

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COVID-19 Transmission in US Child Care Programs
Walter S. Gilliam, Amyn A. Malik, Mehr Shafiq, Madeline Klotz, Chin Reyes, John Eric Humphries, Thomas Murray, Jad A. Elharake, David Wilkinson, Saad B. Omer
Pediatrics Jan 2021, 147 (1) e2020031971; DOI: 10.1542/peds.2020-031971
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