Long-term Outcomes of Individuals With Metabolic Diseases Identified Through Newborn Screening

Dr Mütze conceptualized and designed the study and the data collection instruments, coordinated and supervised data collection, evaluated and interpreted data, drafted the initial manuscript, reviewed and revised the final manuscript, had full access to all the data in the study, and had final responsibility for the decision to submit for publication; Dr Kölker conceptualized and designed the study and the data collection instruments, coordinated and supervised data collection, evaluated and interpreted data, drafted the initial manuscript, and reviewed and revised the final manuscript; Dr Garbade conducted the statistical analyses and critically reviewed and revised the manuscript for important intellectual content; Drs Lindner and Gramer designed the study, collected newborn screening and clinical data, and critically reviewed and revised the manuscript for important intellectual content; Mr Gleich conducted data collection and management and critically reviewed and revised the manuscript for important intellectual content; Drs Freisinger, Hennermann, Ensenauer, Leichsenring, Grünert, Thimm, and Zirnbauer collected the data at their study site and reviewed and critically revised the manuscript for important intellectual content; Drs Hörster, Grohmann-Held, and Boy collected data at the study center and reviewed and revised the manuscript critically for important intellectual content; Dr Fang-Hoffmann collected newborn screening data and reviewed and critically revised the manuscript for important intellectual content; Dr Burgard designed the study, collected clinical data, conducted psychological tests, and critically reviewed and revised the manuscript for important intellectual content; Dr Walter collected clinical data, conducted psychological tests, and critically reviewed and revised the manuscript for important intellectual content; Dr Hoffmann conceptualized and designed the study and critically reviewed and revised the manuscript for important intellectual content; and all authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.