July 2019, VOLUME 144 / ISSUE 1
Table of Contents
- Open AccessEarly Acid Suppression Therapy Exposure and Fracture in Young ChildrenLaura Malchodi, Kari Wagner, Apryl Susi, Gregory Gorman, Elizabeth Hisle-GormanPediatrics Jul 2019, 144 (1) e20182625; DOI: 10.1542/peds.2018-2625
PPI use in infancy, alone or with H2RAs, is associated with fracture after 1 year of age.
- Open AccessAcellular Pertussis Vaccine Effectiveness Over TimeOusseny Zerbo, Joan Bartlett, Kristin Goddard, Bruce Fireman, Edwin Lewis, Nicola P. KleinPediatrics Jul 2019, 144 (1) e20183466; DOI: 10.1542/peds.2018-3466
Compared with children fully DTaP vaccinated, unvaccinated and undervaccinated children were at a greater risk of pertussis. However, most pertussis cases occurred among age-appropriately vaccinated children.
- Open AccessIncidence of Herpes Zoster Among Children: 2003–2014Sheila Weinmann, Allison L. Naleway, Padma Koppolu, Roger Baxter, Edward A. Belongia, Simon J. Hambidge, Stephanie A. Irving, Michael L. Jackson, Nicola P. Klein, Bruno Lewin, Elizabeth Liles, Mona Marin, Ning Smith, Eric Weintraub, Colleen ChunPediatrics Jul 2019, 144 (1) e20182917; DOI: 10.1542/peds.2018-2917
Using data from 6 health care organizations, we examined herpes zoster (HZ) incidence among children in the varicella vaccine era (2003–2014).
- Open AccessImplementing Evidence-Based Strategies to Improve HPV Vaccine DeliveryMelissa B. Gilkey, Michael J. Parks, Marjorie A. Margolis, Annie-Laurie McRee, Jason V. TerkPediatrics Jul 2019, 144 (1) e20182500; DOI: 10.1542/peds.2018-2500
The experience of a large, not-for-profit health care system suggests that local adaptation may be effective in engaging physicians in HPV vaccine–related QI efforts.
- Open AccessMental Health Problems and Initiation of E-cigarette and Combustible Cigarette UseKira E. Riehm, Andrea S. Young, Kenneth A. Feder, Noa Krawczyk, Kayla N. Tormohlen, Lauren R. Pacek, Ramin Mojtabai, Rosa M. CrumPediatrics Jul 2019, 144 (1) e20182935; DOI: 10.1542/peds.2018-2935
Data from a nationally representative sample of youth were used to explore associations between mental health problems and initiation of e-cigarette and combustible cigarette use.
- Open AccessA Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial InfectionPaul L. Aronson, Veronika Shabanova, Eugene D. Shapiro, Marie E. Wang, Lise E. Nigrovic, Christopher M. Pruitt, Adrienne G. DePorre, Rianna C. Leazer, Sanyukta Desai, Laura F. Sartori, Richard D. Marble, Sahar N. Rooholamini, Russell J. McCulloh, Christopher Woll, Fran Balamuth, Elizabeth R. Alpern, Samir S. Shah, Derek J. Williams, Whitney L. Browning, Nipam Shah, Mark I. Neuman, for the Febrile Young Infant Research CollaborativePediatrics Jul 2019, 144 (1) e20183604; DOI: 10.1542/peds.2018-3604
In this multicenter case-control study, we derive and internally validate a highly sensitive score that identifies non–ill-appearing febrile infants at low probability of bacteremia and/or bacterial meningitis.
- Open AccessPrevalence, Risk Factors, and Outcomes of Bacteremic Pneumonia in ChildrenCristin Q. Fritz, Kathryn M. Edwards, Wesley H. Self, Carlos G. Grijalva, Yuwei Zhu, Sandra R. Arnold, Jonathan A. McCullers, Krow Ampofo, Andrew T. Pavia, Richard G. Wunderink, Evan J. Anderson, Anna M. Bramley, Seema Jain, Derek J. WilliamsPediatrics Jul 2019, 144 (1) e20183090; DOI: 10.1542/peds.2018-3090
Using systematic, prospective blood culture collection in children admitted with CAP, this study identifies risk factors and characterizes outcomes associated with bacteremia.
- Open AccessInfant Deaths in Sitting DevicesPeter Liaw, Rachel Y. Moon, Autumn Han, Jeffrey D. ColvinPediatrics Jul 2019, 144 (1) e20182576; DOI: 10.1542/peds.2018-2576
This study uses a nationwide data set to compare risk factors for sleep-related infant deaths occurring in sitting devices and in nonsitting devices.
- Open AccessSafety Interventions and Liquid Laundry Detergent Packet ExposuresChristopher E. Gaw, Henry A. Spiller, Marcel J. Casavant, Thitphalak Chounthirath, Gary A. SmithPediatrics Jul 2019, 144 (1) e20183117; DOI: 10.1542/peds.2018-3117
Liquid laundry detergent packet exposures among children <6 years of age have decreased modestly since 2015, whereas exposures among older children and adults have continued to increase.
- Open AccessHydroxyurea Use for Sickle Cell Disease Among Medicaid-Enrolled ChildrenDavid C. Brousseau, Troy Richardson, Matt Hall, Angela M. Ellison, Samir S. Shah, Jean L. Raphael, David G. Bundy, Staci ArnoldPediatrics Jul 2019, 144 (1) e20183285; DOI: 10.1542/peds.2018-3285
This population-based study of children with SCD assesses trends in hydroxyurea use and associated changes in ED visits and hospitalizations.
- Open AccessPatterns of Electrolyte Testing at Children’s Hospitals for Common Inpatient DiagnosesMichael J. Tchou, Matt Hall, Samir S. Shah, David P. Johnson, Alan R. Schroeder, James W. Antoon, Marquita C. Genies, Ricardo Quinonez, Christopher W. Miller, Snehal P. Shah, Patrick W. Brady, for the Pediatric Research in Inpatient Settings (PRIS) NetworkPediatrics Jul 2019, 144 (1) e20181644; DOI: 10.1542/peds.2018-1644
A retrospective cohort study revealed wide variation in electrolyte testing rates across hospitals, with strong hospital-level correlation across diagnoses.
- Open AccessCervical Spine Injury Risk Factors in Children With Blunt TraumaJulie C. Leonard, Lorin R. Browne, Fahd A. Ahmad, Hamilton Schwartz, Michael Wallendorf, Jeffrey R. Leonard, E. Brooke Lerner, Nathan KuppermannPediatrics Jul 2019, 144 (1) e20183221; DOI: 10.1542/peds.2018-3221
In this multicenter, prospective observational study of 4091 children who experienced blunt trauma, we identified 14 risk factors for CSI.
- Open AccessPalivizumab and Long-term Outcomes in Cystic FibrosisAliza K. Fink, Gavin Graff, Carrie L. Byington, Deena R. Loeffler, Margaret Rosenfeld, Lisa SaimanPediatrics Jul 2019, 144 (1) e20183495; DOI: 10.1542/peds.2018-3495
In this study, we explore palivizumab’s potential benefits related to longer-term outcomes (lung function at age 7, first acquisition of Pseudomonas, and hospitalizations) in children with CF.
- Open AccessA 2017 US Reference for Singleton Birth Weight Percentiles Using Obstetric Estimates of GestationIzzuddin M. Aris, Ken P. Kleinman, Mandy B. Belfort, Anjali Kaimal, Emily OkenPediatrics Jul 2019, 144 (1) e20190076; DOI: 10.1542/peds.2019-0076
This study provides an updated birth weight reference by using a more reliable GA estimate and reflects the current sociodemographic composition of the United States.
- Open AccessA Simpler Prediction Rule for Rebound HyperbilirubinemiaPearl W. Chang, Thomas B. NewmanPediatrics Jul 2019, 144 (1) e20183712; DOI: 10.1542/peds.2018-3712
We turned our previous 3-variable clinical prediction rule for rebound hyperbilirubinemia into a simpler 2-variable rule with similarly excellent discrimination.
- Open AccessPhysical Activity and Trajectories of Cardiovascular Health Indicators During Early ChildhoodNicole A. Proudfoot, Sara King-Dowling, John Cairney, Steven R. Bray, Maureen J. MacDonald, Brian W. TimmonsPediatrics Jul 2019, 144 (1) e20182242; DOI: 10.1542/peds.2018-2242
This prospective cohort study examines the longitudinal effects of physical activity on cardiovascular fitness, arterial stiffness, and blood pressure over 3 years during early childhood.
- Open AccessMental Illness Among Youth With Chronic Physical ConditionsJohn S. Adams, Alyna T. Chien, Lauren E. WiskPediatrics Jul 2019, 144 (1) e20181819; DOI: 10.1542/peds.2018-1819
This nationally representative cohort study examines the risk of mental health diagnosis among youth with CPCs and explores the mediating role of activity limitations.
- Open AccessAdolescent Connectedness and Adult Health OutcomesRiley J. Steiner, Ganna Sheremenko, Catherine Lesesne, Patricia J. Dittus, Renee E. Sieving, Kathleen A. EthierPediatrics Jul 2019, 144 (1) e20183766; DOI: 10.1542/peds.2018-3766
Using the National Longitudinal Study of Adolescent to Adult Health, we document long-term protective associations between family and school connectedness and multiple health outcomes.
- Open AccessFactors Associated With Management of Pediatric Ovarian NeoplasmsAmy E. Lawrence, Dani O. Gonzalez, Mary E. Fallat, Jennifer H. Aldrink, Geri D. Hewitt, S. Paige Hertweck, Amanda Onwuka, Christina Bence, Robert C. Burns, Patrick A. Dillon, Peter F. Ehrlich, Jason D. Fraser, Julia E. Grabowski, Ronald B. Hirschl, Rashmi Kabre, Jonathan E. Kohler, Dave R. Lal, Matthew P. Landman, Charles M. Leys, Grace Z. Mak, Thomas T. Sato, Madeline Scannell, Joseph A. Sujka, Peter C. Minneci, Katherine J. DeansPediatrics Jul 2019, 144 (1) e20182537; DOI: 10.1542/peds.2018-2537
Through retrospective review of >800 patients, we describe the current approach to ovarian masses, both benign and malignant, in the pediatric patient.
- Open AccessNeurologic Outcome After Prematurity: Perspectives of Parents and CliniciansMonica E. Lemmon, Hanna Huffstetler, Mary Carol Barks, Christine Kirby, Madelaine Katz, Peter A. Ubel, Sharron L. Docherty, Debra BrandonPediatrics Jul 2019, 144 (1) e20183819; DOI: 10.1542/peds.2018-3819
This qualitative descriptive study illustrates that parents and clinicians discuss and weigh prognostic information differently from each other as they consider choices for premature infants.
- Open AccessSocial Robots for Hospitalized ChildrenDeirdre E. Logan, Cynthia Breazeal, Matthew S. Goodwin, Sooyeon Jeong, Brianna O’Connell, Duncan Smith-Freedman, James Heathers, Peter WeinstockPediatrics Jul 2019, 144 (1) e20181511; DOI: 10.1542/peds.2018-1511
SRs offer unique opportunities to extend emotionally responsive care among limited human resources. We explore feasibility and acceptability of integrating SR technology into pediatric health care.
- Open AccessDefining Global Health Tracks for Pediatric ResidenciesHeather Haq, Adelaide Barnes, Maneesh Batra, Tania Condurache, Michael B. Pitt, Jeff A. Robison, Chuck Schubert, Nicole St Clair, Omolara Uwemedimo, Jennifer Watts, Christiana M. RussPediatrics Jul 2019, 144 (1) e20183860; DOI: 10.1542/peds.2018-3860
We present a consensus definition, minimal educational offerings and institutional supports, and evaluation methods for a GH track in pediatric residency using Delphi methodology.
- Open AccessCharacteristics and Workload of Pediatricians in ChinaYongjun Zhang, Lisu Huang, Xin Zhou, Xi Zhang, Zheng Ke, Zhaoxi Wang, Qiang Chen, Xiangyu Dong, Lizhong Du, Jianpei Fang, Xing Feng, Jianhua Fu, Zhixu He, Guoying Huang, Songming Huang, Xiuli Ju, Li Gao, Li Li, Tingyu Li, Yarui Li, Geli Liu, Wenjun Liu, Xiaoping Luo, Guangming Nong, Jiahua Pan, Kunling Shen, Hongmei Song, Jinghui Sun, Dezhi Mu, Tianyou Wang, Baoxi Wang, Wei Xiang, Changyi Yang, Shufen Yang, Zhengyan Zhao, Hua Zhu, Yimin Zhu, Jun Zhang, Julian Little, Therese Hesketh, Kun SunPediatrics Jul 2019, 144 (1) e20183532; DOI: 10.1542/peds.2018-3532
Through a national survey, we found that uneven development of the pediatric care system is the major challenge facing China’s pediatric health care system.
- Open AccessAcid Suppression Therapy and Symptom Improvement (or Lack Thereof) in ChildrenMary Boruta, Richard Boruta, Jennifer LiPediatrics Jul 2019, 144 (1) e20190909; DOI: 10.1542/peds.2019-0909
- Open AccessPrediction Models for Febrile Infants: Time for a Unified Field TheoryNathan Kuppermann, Prashant Mahajan, Octavio RamiloPediatrics Jul 2019, 144 (1) e20191375; DOI: 10.1542/peds.2019-1375
From the American Academy of Pediatrics
- Open AccessElectronic Communication of the Health Record and Information With Pediatric Patients and Their GuardiansEmily C. Webber, David Brick, James P. Scibilia, Peter Dehnel, COUNCIL ON CLINICAL INFORMATION TECHNOLOGY, COMMITTEE ON MEDICAL LIABILITY AND RISK MANAGEMENT, SECTION ON TELEHEALTH CAREPediatrics Jul 2019, 144 (1) e20191359; DOI: 10.1542/peds.2019-1359
- Open AccessLet Them Breathe: A Plea to Pediatricians to Advocate for Stock Inhaler Policies at SchoolAndrea A. Pappalardo, Lynn B. GeraldPediatrics Jul 2019, 144 (1) e20182857; DOI: 10.1542/peds.2018-2857
- Open AccessThe Right Stuff: Priming Students to Focus on Pertinent Information During Clinical EncountersElizabeth Stuart, Janice L. Hanson, Robert Arthur DudasPediatrics Jul 2019, 144 (1) e20191311; DOI: 10.1542/peds.2019-1311
In this article, we offer a framework for coaching students to understand clinical relevance and increase efficiency in patient care.
- Open AccessNeurodevelopmental and Academic Outcomes in Children With Orofacial Clefts: A Systematic ReviewEmily R. Gallagher, Brent R. CollettPediatrics Jul 2019, 144 (1) e20184027; DOI: 10.1542/peds.2018-4027
In this systematic review, we examine the findings that children with OFCs have worse neurodevelopmental and academic outcomes compared with unaffected peers, examining trends by age.
- Open AccessOmega-3 Long-chain Polyunsaturated Fatty Acids for Bronchopulmonary Dysplasia: A Meta-analysisQian Wang, Bing Zhou, Qiliang Cui, Chao ChenPediatrics Jul 2019, 144 (1) e20190181; DOI: 10.1542/peds.2019-0181
With this meta-analysis, we provide a new perspective on the association between N-3 LCPUFA intervention and incidence of BPD in preterm infants.
State-of-the-Art Review Article
- Open AccessContinuous Noninvasive Carbon Dioxide Monitoring in Neonates: From Theory to Standard of CareOri Hochwald, Liron Borenstein-Levin, Gil Dinur, Huda Jubran, Shlomit Ben-David, Amir KugelmanPediatrics Jul 2019, 144 (1) e20183640; DOI: 10.1542/peds.2018-3640
We review the different noninvasive CO2 monitoring alternatives, their advantages and disadvantages, and the available data supporting their use as a standard of care in NICUs.
- Open AccessSpread of Measles in Europe and Implications for US TravelersKristina M. Angelo, Paul A. Gastañaduy, Allison T. Walker, Manisha Patel, Susan Reef, C. Virginia Lee, Jeffrey NemhauserPediatrics Jul 2019, 144 (1) e20190414; DOI: 10.1542/peds.2019-0414
The record number of measles cases in the WHO European Region puts both international travelers and nontraveling US residents at risk for measles.
- Open AccessFirearm Injuries and Children: Position Statement of the American Pediatric Surgical AssociationJohn K. Petty, Marion C.W. Henry, Michael L. Nance, Henri R. Ford, APSA Board of GovernorsPediatrics Jul 2019, 144 (1) e20183058; DOI: 10.1542/peds.2018-3058
The increase in firearm injuries affects all pediatric care providers. The APSA recommends improved trauma care, research, prevention, and policy to address this public health problem.
- Open AccessAllowing Adolescents to Weigh Benefits and Burdens of High-stakes TherapiesKriti Puri, Janet Malek, Caridad Maylin de la Uz, John Lantos, Antonio Gabriel Cabrera, Ernest FrugéPediatrics Jul 2019, 144 (1) e20183714; DOI: 10.1542/peds.2018-3714
In this case study, we discuss the ethical considerations when there is discordance between an adolescent close to attaining age of majority and the parent currently responsible for medical decision-making in a high-risk medical setting.
- Open AccessFive-Year Outcomes of Behavioral Health Integration in Pediatric Primary CareHeather J. Walter, Louis Vernacchio, Emily K. Trudell, Jonas Bromberg, Ellen Goodman, Jessica Barton, Gregory J. Young, David R. DeMaso, Glenn FochtPediatrics Jul 2019, 144 (1) e20183243; DOI: 10.1542/peds.2018-3243
In this study, we describe the 5-year outcomes of BH integration in a large pediatric primary care network in patient experience, cost, and provider satisfaction domains.
- Open AccessAddressing Disparities in Mother’s Milk for VLBW Infants Through Statewide Quality ImprovementMargaret G. Parker, Laura A. Burnham, Patrice Melvin, Rachana Singh, Adriana M. Lopera, Mandy B. Belfort, James M. Moses, Munish GuptaPediatrics Jul 2019, 144 (1) e20183809; DOI: 10.1542/peds.2018-3809
We report findings from a 3-year Massachusetts statewide QI collaborative that aimed to improve mother’s milk provision and reduce racial and ethnic disparities.
- Open AccessHypotonia and Lethargy in a Two-Day-Old Male InfantAdrienne H. Long, Jennifer G. Fiore, Riaz Gillani, Laurie M. Douglass, Alan M. Fujii, Jodi D. HoffmanPediatrics Jul 2019, 144 (1) e20180788; DOI: 10.1542/peds.2018-0788
The case of a 2-day-old term male infant found in the newborn nursery to be hypotonic and minimally reactive is discussed.
- Open AccessSuspicion and Persistence: A Case of Pediatric Brugada SyndromeBrynn E. Dechert, Martin J. LaPage, Mitchell I. CohenPediatrics Jul 2019, 144 (1) e20183296; DOI: 10.1542/peds.2018-3296
This case study highlights the difficulty in diagnosing Brugada syndrome in a young patient with a normal electrocardiogram result at baseline.
- Open AccessSacral Myeloradiculitis: An Uncommon Complication of Genital Herpes InfectionAllison M. Whalen, Camila M. Mateo, Amanda S. Growdon, Andrew F. MillerPediatrics Jul 2019, 144 (1) e20182631; DOI: 10.1542/peds.2018-2631
An 18-year-old man with genital HSV infection presents with constipation, urinary retention, paresthesias, and MRI findings of sacral myeloradiculitis.
- Open AccessInflammatory Arthritis as a Possible Feature of Coffin-Siris SyndromeSonia Melo Gomes, Cristina Dias, Ebun Omoyinmi, Sandrine Compeyrot-Lacassagne, Nigel Klein, Neil J. Sebire, Paul BroganPediatrics Jul 2019, 144 (1) e20181741; DOI: 10.1542/peds.2018-1741
Case report of a young boy with true inflammatory arthritis and diagnosis of CSS. Inflammatory arthritis may be under-recognized in chromatin remodeling–associated genetic syndromes.
- Open AccessHollis BW, Wagner CL, Howard CR, et al. Maternal Versus Infant Vitamin D Supplementation During Lactation: A Randomized Controlled Trial. Pediatrics. 2015;136(4):625–634Pediatrics Jul 2019, 144 (1) e20191063; DOI: 10.1542/peds.2019-1063
- Open AccessTieder JS, Bonkowsky JL, Etzel RA, et al; Subcommittee on Apparent Life Threatening Events. Clinical Practice Guideline: Brief Resolved Unexplained Events (Formerly Apparent Life-Threatening Events) and Evaluation of Lower-Risk Infants. Pediatrics. 2016;137(5):e20160590Pediatrics Jul 2019, 144 (1) e20191360; DOI: 10.1542/peds.2019-1360