February 2019, VOLUME 143 / ISSUE 2
Table of Contents
- Open AccessHuman Papillomavirus Vaccine Effectiveness and Herd Protection in Young WomenChelse Spinner, Lili Ding, David I. Bernstein, Darron R. Brown, Eduardo L. Franco, Courtney Covert, Jessica A. KahnPediatrics Feb 2019, 143 (2) e20181902; DOI: 10.1542/peds.2018-1902
Over an 11-year period after HPV vaccine introduction, we found in this community-based surveillance study evidence of vaccine effectiveness and herd protection among young women.
- Open AccessQuestions and Concerns About HPV Vaccine: A Communication ExperimentParth D. Shah, William A. Calo, Melissa B. Gilkey, Marcella H. Boynton, Susan Alton Dailey, Karen G. Todd, Meagan O. Robichaud, Marjorie A. Margolis, Noel T. BrewerPediatrics Feb 2019, 143 (2) e20181872; DOI: 10.1542/peds.2018-1872
In this study, we provide brief messages providers can use when discussing HPV vaccination and guidance for more effectively addressing parents’ questions and concerns about HPV vaccination.
- Open AccessFamily Firearm Ownership and Firearm-Related Mortality Among Young Children: 1976–2016Kate C. Prickett, Carmen Gutierrez, Soudeep DebPediatrics Feb 2019, 143 (2) e20181171; DOI: 10.1542/peds.2018-1171
Linking national-level estimates of US firearm ownership and firearm-related mortality, we examined how changes in ownership are associated with firearm-related mortality among young children.
- Open AccessParent-Adolescent Agreement About Adolescents’ Suicidal ThoughtsJason D. Jones, Rhonda C. Boyd, Monica E. Calkins, Annisa Ahmed, Tyler M. Moore, Ran Barzilay, Tami D. Benton, Raquel E. GurPediatrics Feb 2019, 143 (2) e20181771; DOI: 10.1542/peds.2018-1771
We found substantial discrepancies between adolescent and parent reports of adolescents’ suicidal thoughts in a sample of 5137 adolescents recruited from a pediatric health care network.
- Open AccessAntibiotic Prescribing for Children in United States Emergency Departments: 2009–2014Nicole M. Poole, Daniel J. Shapiro, Katherine E. Fleming-Dutra, Lauri A. Hicks, Adam L. Hersh, Matthew P. KronmanPediatrics Feb 2019, 143 (2) e20181056; DOI: 10.1542/peds.2018-1056
Using a nationally representative database of nonfederal EDs, we provide the first comprehensive overview of antibiotic prescribing for children in pediatric and nonpediatric EDs.
- Open AccessLive Attenuated and Inactivated Influenza Vaccine EffectivenessJessie R. Chung, Brendan Flannery, Christopher S. Ambrose, Rodolfo E. Bégué, Herve Caspard, Laurie DeMarcus, Ashley L. Fowlkes, Geeta Kersellius, Andrea Steffens, Alicia M. Fry, for the Influenza Clinical Investigation for Children Study Team, the Influenza Incidence Surveillance Project, the US Influenza Vaccine Effectiveness NetworkPediatrics Feb 2019, 143 (2) e20182094; DOI: 10.1542/peds.2018-2094
In a combined analysis from 5 studies, LAIV4 was less effective than IIV against influenza A/H1N1pdm09 in all pediatric age groups.
- Open AccessTobacco Retail Licensing and Youth Product UseRoee L. Astor, Robert Urman, Jessica L. Barrington-Trimis, Kiros Berhane, Jane Steinberg, Michael Cousineau, Adam M. Leventhal, Jennifer B. Unger, Tess Cruz, Mary Ann Pentz, Jonathan M. Samet, Rob McConnellPediatrics Feb 2019, 143 (2) e20173536; DOI: 10.1542/peds.2017-3536
Strong TRL ordinances used to reduce youth access were associated with lower rates of cigarette and e-cigarette use in young adult life.
- Open AccessPriorities for Pediatric Patient Safety ResearchJames M. Hoffman, Nicholas J. Keeling, Christopher B. Forrest, Heather L. Tubbs-Cooley, Erin Moore, Emily Oehler, Stephanie Wilson, Elisabeth Schainker, Kathleen E. WalshPediatrics Feb 2019, 143 (2) e20180496; DOI: 10.1542/peds.2018-0496
The nation’s largest network devoted to preventing harm in pediatrics used consensus methods to develop a list of priorities for patient-safety research in children.
- Open AccessBarriers and Stigma Experienced by Gay Fathers and Their ChildrenEllen C. Perrin, Sean M. Hurley, Kathryn Mattern, Lila Flavin, Ellen E. PinderhughesPediatrics Feb 2019, 143 (2) e20180683; DOI: 10.1542/peds.2018-0683
Pathways to fatherhood for gay men have increased and changed. They and their children continue to experience and anticipate stigma in many social contexts.
- Open AccessDiscussion of Potentially Sensitive Topics With Young PeopleJohn S. Santelli, Jonathan D. Klein, Xiaoyu Song, Jennifer Heitel, Stephanie Grilo, Mengru Wang, Hanying Yan, Kristen Kaseeska, Julie Gorzkowski, Madeline Schneider, Alexandra E. Dereix, Marina CatallozziPediatrics Feb 2019, 143 (2) e20181403; DOI: 10.1542/peds.2018-1403
We identify factors associated with discussions between health care providers and AYAs and suggest ways for providers to improve delivery of preventive services.
- Open AccessContraceptive Initiation Among Women in the United States: Timing, Methods Used, and Pregnancy OutcomesMara E. Murray Horwitz, Dennis Ross-Degnan, Lydia E. PacePediatrics Feb 2019, 143 (2) e20182463; DOI: 10.1542/peds.2018-2463
In this study, we analyze 45-year trends in timing and type of contraceptive initiation among US women and assess the association between delayed initiation and unwanted pregnancy.
- Open AccessCognitive Outcomes and Positional PlagiocephalyBrent R. Collett, Erin R. Wallace, Deborah Kartin, Michael L. Cunningham, Matthew L. SpeltzPediatrics Feb 2019, 143 (2) e20182373; DOI: 10.1542/peds.2018-2373
In this prospective cohort study, we examine cognitive and academic outcomes in children with and without a history of PPB.
- Open AccessPerinatal Risk Factors and Outcome Coding in Clinical and Administrative DatabasesDaniel S. Tawfik, Jeffrey B. Gould, Jochen ProfitPediatrics Feb 2019, 143 (2) e20181487; DOI: 10.1542/peds.2018-1487
Through linkage of statewide administrative and clinical perinatal databases, we highlight risk factors and outcomes with high accuracy, as well as targets for data quality improvement.
- Open AccessFactors Associated With Rotavirus Vaccine CoverageNegar Aliabadi, Mary E. Wikswo, Jacqueline E. Tate, Margaret M. Cortese, Peter G. Szilagyi, Mary Allen Staat, Geoffrey A. Weinberg, Natasha B. Halasa, Julie A. Boom, Rangaraj Selvarangan, Janet A. Englund, Parvin H. Azimi, Eileen J. Klein, Mary E. Moffatt, Christopher J. Harrison, Leila C. Sahni, Laura S. Stewart, David I. Bernstein, Umesh D. Parashar, Daniel C. PaynePediatrics Feb 2019, 143 (2) e20181824; DOI: 10.1542/peds.2018-1824
In an analysis of a nationwide active surveillance system, we identified factors associated with low coverage and missed opportunities for the initiation and completion of the RVV series.
- Open AccessRetinal Findings in Young Children With Increased Intracranial Pressure From Nontraumatic CausesAngell Shi, Abhaya Kulkarni, Kenneth W. Feldman, Avery Weiss, Emily A. McCourt, Susan Schloff, Michael Partington, Brian Forbes, Brooke E. Geddie, Karin Bierbrauer, Paul H. Phillips, David L. Rogers, Waleed Abed Alnabi, Gil Binenbaum, Alex V. LevinPediatrics Feb 2019, 143 (2) e20181182; DOI: 10.1542/peds.2018-1182
In this study, we report an absence of RHs in young children with increased ICP.
- Open AccessNewborn Risk Factors for Subsequent Physical Abuse HospitalizationsHenry T. Puls, James D. Anderst, Jessica L. Bettenhausen, Nicholas Clark, Molly Krager, Jessica L. Markham, Matthew HallPediatrics Feb 2019, 143 (2) e20182108; DOI: 10.1542/peds.2018-2108
In this study, we identify perinatal risk factors and newborn populations with multiple risk factors who have the greatest risk for physical abuse; implications for prevention are discussed.
- Open AccessDevelopment and Validation of a Cellulitis Risk Score: The Melbourne ASSET ScoreLaila F. Ibrahim, Sandy M. Hopper, Susan Donath, Bennett Salvin, Franz E. Babl, Penelope A. BryantPediatrics Feb 2019, 143 (2) e20181420; DOI: 10.1542/peds.2018-1420
The Melbourne ASSET Risk Score was developed to aid clinicians in deciding whether to treat cellulitis with IV antibiotics.
- Open AccessSurvival and Health Care Use After Feeding Tube Placement in Children With Neurologic ImpairmentKatherine E. Nelson, Laura C. Rosella, Sanjay Mahant, Eyal Cohen, Astrid GuttmannPediatrics Feb 2019, 143 (2) e20182863; DOI: 10.1542/peds.2018-2863
Using population-based data from Ontario, we evaluate survival after feeding tube placement and acute health care use 2 years before and after the procedure.
- Open AccessAdolescent Mental Health and the Choking GameGrégory Michel, Mathieu Garcia, Valérie Aubron, Sabrina Bernadet, Julie Salla, Diane Purper-OuakilPediatrics Feb 2019, 143 (2) e20173963; DOI: 10.1542/peds.2017-3963
In this article, we examine the contribution of conduct problems, depressive symptoms, and risk behaviors to CG participation in middle school students.
- Open AccessBifidobacterium Abundance in Early Infancy and Vaccine Response at 2 Years of AgeM. Nazmul Huda, Shaikh M. Ahmad, M. Jahangir Alam, Afsana Khanam, Karen M. Kalanetra, Diana H. Taft, Rubhana Raqib, Mark A. Underwood, David A. Mills, Charles B. StephensenPediatrics Feb 2019, 143 (2) e20181489; DOI: 10.1542/peds.2018-1489
By following a birth cohort through 2 years of age, Bifidobacterium abundance in early infancy was seen to predict better vaccine responses later in life.
- Open AccessAcceptance and Commitment Therapy for Parental Management of Childhood Asthma: An RCTYuen-yu Chong, Yim-wah Mak, Sui-ping Leung, Shu-yan Lam, Alice Yuen LokePediatrics Feb 2019, 143 (2) e20181723; DOI: 10.1542/peds.2018-1723
Through an RCT, we show that ACT plus asthma education for parents improves their psychological well-being and children’s asthma outcomes.
- Open AccessPromoting Enrollment in Parenting Programs Among a Filipino Population: A Randomized TrialJoyce R. Javier, Dean M. Coffey, Lawrence A. Palinkas, Michele D. Kipke, Jeanne Miranda, Sheree M. SchragerPediatrics Feb 2019, 143 (2) e20180553; DOI: 10.1542/peds.2018-0553
We present results of a randomized controlled trial aimed at evaluating the effects of a culturally tailored video on enrollment in evidence-based parenting interventions.
- Open AccessNewborn Screening for Severe Combined Immunodeficiency and T-cell Lymphopenia in California, 2010–2017George S. Amatuni, Robert J. Currier, Joseph A. Church, Tracey Bishop, Elena Grimbacher, Alan Anh-Chuong Nguyen, Rajni Agarwal-Hashmi, Constantino P. Aznar, Manish J. Butte, Morton J. Cowan, Morna J. Dorsey, Christopher C. Dvorak, Neena Kapoor, Donald B. Kohn, M. Louise Markert, Theodore B. Moore, Stanley J. Naides, Stanley Sciortino, Lisa Feuchtbaum, Rasoul A. Koupaei, Jennifer M. PuckPediatrics Feb 2019, 143 (2) e20182300; DOI: 10.1542/peds.2018-2300
NBS has improved the detection, diagnosis, treatment, and basic understanding of SCID; infants with TCL are also detected, facilitating management.
- Open AccessTrends in Pediatric Hospitalizations and Readmissions: 2010–2016Emily M. Bucholz, Sara L. Toomey, Mark A. SchusterPediatrics Feb 2019, 143 (2) e20181958; DOI: 10.1542/peds.2018-1958
Using data from a nationwide sample of pediatric discharges, we examine trends in pediatric hospitalizations and readmissions from 2010 to 2016.
- Open AccessPatterns of Prenatal Alcohol Use That Predict Infant Growth and DevelopmentGretchen Bandoli, Claire D. Coles, Julie A. Kable, Wladimir Wertelecki, Lyubov Yevtushok, Natalya Zymak-Zakutnya, Alan Wells, Irina V. Granovska, Alla O. Pashtepa, Christina D. Chambers, the CIFASDPediatrics Feb 2019, 143 (2) e20182399; DOI: 10.1542/peds.2018-2399
In this study, we use longitudinal trajectory methods to distinguish patterns of prenatal alcohol use and determine if patterns are used to predict deficits in growth or neurodevelopment in offspring.
- Open AccessCaregiver Experience in Pediatric DialysisAaron Wightman, Cortney Taylor Zimmerman, Shari Neul, Katherine Lepere, KristiLynn Cedars, Douglas OpelPediatrics Feb 2019, 143 (2) e20182102; DOI: 10.1542/peds.2018-2102
In this study, we describe caregiver experience in pediatric chronic dialysis using a thematic analysis of interviews of caregivers at 3 centers.
- Open AccessNeurodevelopmental Impairments 1 Year After Cerebral MalariaJohn T. Langfitt, Michael P. McDermott, Rachel Brim, Sebastian Mboma, Michael J. Potchen, Sam D. Kampondeni, Karl B. Seydel, Margaret Semrud-Clikeman, Terrie E. TaylorPediatrics Feb 2019, 143 (2) e20181026; DOI: 10.1542/peds.2018-1026
Neurodevelopmental impairments persist at 1-year assessments in one-half of the survivors of CM and are associated with HIV, stunting, severity of illness, and MRI abnormalities.
- Open AccessContinuous Versus Intermittent Vancomycin Infusions in Infants: A Randomized Controlled TrialAmanda Gwee, Noel Cranswick, Brendan McMullan, Elizabeth Perkins, Srinivas Bolisetty, Kaya Gardiner, Andrew Daley, Meredith Ward, Roberto Chiletti, Susan Donath, Rodney Hunt, Nigel CurtisPediatrics Feb 2019, 143 (2) e20182179; DOI: 10.1542/peds.2018-2179
In this RCT of CIV and IIV in young infants, we compared the attainment of target vancomycin concentrations and drug-related adverse effects.
- Open AccessEffects of Feedback on Chest Compression Quality: A Randomized Simulation StudyMichael Wagner, Katharina Bibl, Emilie Hrdliczka, Philipp Steinbauer, Maria Stiller, Peter Gröpel, Katharina Goeral, Ulrike Salzer-Muhar, Angelika Berger, Georg M. Schmölzer, Monika OlischarPediatrics Feb 2019, 143 (2) e20182441; DOI: 10.1542/peds.2018-2441
CC performance significantly improved with verbal or visual feedback compared with instructor-led feedback in a randomized, simulation-based pediatric resuscitation training.
- Open Access“Smart” Choices: Shared Decision-making in Firearm Storage and Personalized FirearmsShilpa J. Patel, Monika K. Goyal, Kavita ParikhPediatrics Feb 2019, 143 (2) e20183611; DOI: 10.1542/peds.2018-3611
- Open AccessParent-Adolescent Agreement About Adolescent’s Suicidal Thoughts: A DivergenceKhyati Brahmbhatt, Jacqueline Grupp-PhelanPediatrics Feb 2019, 143 (2) e20183071; DOI: 10.1542/peds.2018-3071
- Open AccessImproving Antimicrobial Stewardship in Pediatric Emergency Care: A Pathway ForwardRakesh D. Mistry, Larissa S. May, Michael S. PuliaPediatrics Feb 2019, 143 (2) e20182972; DOI: 10.1542/peds.2018-2972
- Open AccessRepurposing of Administrative Data for Research: Still Useful but for How Much Longer?Paul L. Hebert, Jodie G. KatonPediatrics Feb 2019, 143 (2) e20183293; DOI: 10.1542/peds.2018-3293
- Open AccessFeeding Tubes in Children With Neurologic Impairment: An Opportunity for Shared Decision-makingK. Jane Lee, Timothy E. CordenPediatrics Feb 2019, 143 (2) e20183623; DOI: 10.1542/peds.2018-3623
From the American Academy of Pediatrics
- Open AccessPrinciples of Pediatric Patient Safety: Reducing Harm Due to Medical CareBrigitta U. Mueller, Daniel Robert Neuspiel, Erin R. Stucky Fisher, COUNCIL ON QUALITY IMPROVEMENT AND PATIENT SAFETY, COMMITTEE ON HOSPITAL CAREPediatrics Feb 2019, 143 (2) e20183649; DOI: 10.1542/peds.2018-3649
- Open AccessThe Pivotal Role of the International Medical GraduateRana Chakraborty, Mobeen H. Rathore, Benard P. Dreyer, Fernando SteinPediatrics Feb 2019, 143 (2) e20181189; DOI: 10.1542/peds.2018-1189
Advocacy Case Study
- Open AccessLeveraging Evidence-Based Public Policy and Advocacy to Advance Newborn Screening in CaliforniaMax G. Bronstein, Richard J. Pan, Mark Dant, Bertrand LubinPediatrics Feb 2019, 143 (2) e20181886; DOI: 10.1542/peds.2018-1886
We provide insight into advancing state newborn screening. We explain how to leverage public policy to advance screening for new diseases.
- Open AccessSyrian Children in Turkey: A Model of Action for National Pediatric SocietiesElif N. Özmert, Orhan Derman, Aysun Bideci, Nurullah Okumuş, Koray Boduroğlu, Sevcan Bakkaloğlu, Enver Hasanoğlu, Errol AldenPediatrics Feb 2019, 143 (2) e20180539; DOI: 10.1542/peds.2018-0539
- Open AccessSurvival and Impairment of Extremely Premature Infants: A Meta-analysisHilde Tinderholt Myrhaug, Kjetil Gundro Brurberg, Laila Hov, Trond MarkestadPediatrics Feb 2019, 143 (2) e20180933; DOI: 10.1542/peds.2018-0933
The survival rates increased and the risk of survival with severe impairments decreased for every additional week of GA among infants born extremely premature.
State-of-the-Art Review Article
- Open AccessEthical Implications for Providers Regarding Cannabis Use in Children With Autism Spectrum DisordersSusanne W. Duvall, Olivia Lindly, Katharine Zuckerman, Michael E. Msall, Melissa WeddlePediatrics Feb 2019, 143 (2) e20180558; DOI: 10.1542/peds.2018-0558
Given the recent legalization of cannabis for medical and/or recreational use in many states, ethical implications about usage in children with ASD are discussed.
- Open AccessThe 2018 Joseph W. St. Geme, Jr. Leadership Award Address: Reflections on MentorshipMark A. SchusterPediatrics Feb 2019, 143 (2) e20182957; DOI: 10.1542/peds.2018-2957
Drawing from his mentoring experiences and from current research on mentorship (supplemented with lessons from Yoda), the author proposes policies supporting mentorship in academic medicine.
- Open AccessAddressing Racial Inequities in Breastfeeding in the Southern United StatesAnne Merewood, Kimarie Bugg, Laura Burnham, Kirsten Krane, Nathan Nickel, Sarah Broom, Roger Edwards, Lori Feldman-WinterPediatrics Feb 2019, 143 (2) e20181897; DOI: 10.1542/peds.2018-1897
The CHAMPS project was used to address racial inequities in breastfeeding in the Southern United States by implementing practice changes based on the Ten Steps to Successful Breastfeeding.
- Open AccessQuality Improvement Project to Decrease Delivery Room Intubations in Preterm InfantsVenkatakrishna Kakkilaya, Ihab Jubran, Vaishali Mashruwala, Emma Ramon, Valerie N. Simcik, Marjory Marshall, L. Steven Brown, Mambarambath A. Jaleel, Vishal S. KapadiaPediatrics Feb 2019, 143 (2) e20180201; DOI: 10.1542/peds.2018-0201
We discuss implementation of a resuscitation bundle aimed at improving Fm-PPV to decrease the DRI rate of preterm infants.
- Open AccessRanitidine-Induced Delirium in a 7-Year-Old Girl: A Case ReportRoberta Esteves Vieira de Castro, Carolina da Cunha Sousa, Maria Clara de Magalhães-Barbosa, Arnaldo Prata-Barbosa, Elie CheniauxPediatrics Feb 2019, 143 (2) e20182428; DOI: 10.1542/peds.2018-2428
This case study reveals the risk of development of delirium in children due to anticholinergic toxidrome secondary to the use of ranitidine.
- Open AccessMethemoglobinemia in an Infant After Sclerotherapy With High-Dose DoxycyclineKatherine Coughlin, John Flibotte, Anne Marie Cahill, Kevin Osterhoudt, Holly Hedrick, Jesse VrecenakPediatrics Feb 2019, 143 (2) e20181642; DOI: 10.1542/peds.2018-1642
A case of persistent desaturation in an infant with a cervical lymphangioma in the setting of treatment with sclerotherapy is examined.
- Open AccessMutation in ITCH Gene Can Cause Syndromic Multisystem Autoimmune Disease With Acute Liver FailureNicola Kleine-Eggebrecht, Christian Staufner, Simone Kathemann, Magdeldin Elgizouli, Robert Kopajtich, Holger Prokisch, Elke LainkaPediatrics Feb 2019, 143 (2) e20181554; DOI: 10.1542/peds.2018-1554
Mutations in the ITCH gene can cause severe SMAD, which is a possible cause of acute liver failure requiring an LT.
- Open AccessFreire G, Kuppermann N, Zemek R, et al; Pediatric Emergency Research Networks (PERN). Predicting Escalated Care in Infants With Bronchiolitis. Pediatrics. 2018;142(3):e20174253Pediatrics Feb 2019, 143 (2) e20183404; DOI: 10.1542/peds.2018-3404
- Open AccessBlock JP, Bailey LC, Gillman MW, et al; PCORnet Antibiotics and Childhood Growth Study Group. Early Antibiotic Exposure and Weight Outcomes in Young Children. Pediatrics. 2018;142(6):e20180290Pediatrics Feb 2019, 143 (2) e20183555; DOI: 10.1542/peds.2018-3555
- Open AccessSege RD, Siegel BS; Council on Child Abuse and Neglect; Committee on Psychosocial Aspects of Child and Family Health. Effective Discipline to Raise Healthy Children. Pediatrics. 2018;142(6):e20183112Pediatrics Feb 2019, 143 (2) e20183609; DOI: 10.1542/peds.2018-3609
- Open AccessWhite PH, Cooley WC; Transitions Clinical Report Authoring Group; American Academy of Pediatrics; American Academy of Family Physicians; American College of Physicians. Supporting the Health Care Transition From Adolescence to Adulthood in the Medical Home. Pediatrics. 2018;142(5):e20182587Pediatrics Feb 2019, 143 (2) e20183610; DOI: 10.1542/peds.2018-3610
- Open AccessJackson SL, Yang EC, Zhang Z. Income Disparities and Cardiovascular Risk Factors Among Adolescents. Pediatrics. 2018;142(5):e20181089Pediatrics Feb 2019, 143 (2) e20183644; DOI: 10.1542/peds.2018-3644