May 2018, VOLUME 141 / ISSUE 5
Table of Contents
- Open AccessDisparities for LGBTQ and Gender Nonconforming AdolescentsLaura BaamsPediatrics May 2018, 141 (5) e20173004; DOI: 10.1542/peds.2017-3004
By examining experiences of household dysfunction and abuse, disparities in patterns of adversity (such as polyvictimization) for LGBTQ and gender nonconforming adolescents are identified in this study.
- Open AccessMental Health of Transgender and Gender Nonconforming Youth Compared With Their PeersTracy A. Becerra-Culqui, Yuan Liu, Rebecca Nash, Lee Cromwell, W. Dana Flanders, Darios Getahun, Shawn V. Giammattei, Enid M. Hunkeler, Timothy L. Lash, Andrea Millman, Virginia P. Quinn, Brandi Robinson, Douglas Roblin, David E. Sandberg, Michael J. Silverberg, Vin Tangpricha, Michael GoodmanPediatrics May 2018, 141 (5) e20173845; DOI: 10.1542/peds.2017-3845
The prevalence of mental health conditions among transfeminine and transmasculine youth 3 to 17 years old at initial presentation is estimated and compared with matched cisgender counterparts.
- Open AccessSexual Orientation and Depressive Symptoms in AdolescentsJeremy W. Luk, Stephen E. Gilman, Denise L. Haynie, Bruce G. Simons-MortonPediatrics May 2018, 141 (5) e20173309; DOI: 10.1542/peds.2017-3309
In a recent national cohort, low family satisfaction, cyberbullying victimization, and unmet medical needs were unique contributors to sexual orientation disparities in adolescent depressive symptoms.
- Open AccessElectronic Cigarettes and Future Marijuana Use: A Longitudinal StudyHongying Dai, Delwyn Catley, Kimber P. Richter, Kathy Goggin, Edward F. EllerbeckPediatrics May 2018, 141 (5) e20173787; DOI: 10.1542/peds.2017-3787
In this study, we examined whether e-cigarette use among marijuana never users predicts initiation of ever and heavy marijuana use 1 year later.
- Open AccessE-Cigarette and Liquid Nicotine Exposures Among Young ChildrenPreethi Govindarajan, Henry A. Spiller, Marcel J. Casavant, Thitphalak Chounthirath, Gary A. SmithPediatrics May 2018, 141 (5) e20173361; DOI: 10.1542/peds.2017-3361
Monthly liquid nicotine exposures among US children <6 years old peaked in early 2015. Annual exposure rates decreased by ∼20% from 2015 to 2016.
- Open AccessAntibiotic Use After Removal of Penicillin Allergy LabelDavid Vyles, Asriani Chiu, John Routes, Mariana Castells, Elizabeth J. Phillips, Jennifer Kibicho, David C. BrousseauPediatrics May 2018, 141 (5) e20173466; DOI: 10.1542/peds.2017-3466
Children with penicillin allergy were tested, found to receive negative test results, and, subsequently, tolerated penicillin without serious adverse or allergic reactions.
- Open AccessNeurodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research NetworkIra Adams-Chapman, Roy J. Heyne, Sara B. DeMauro, Andrea F. Duncan, Susan R. Hintz, Athina Pappas, Betty R. Vohr, Scott A. McDonald, Abhik Das, Jamie E. Newman, Rosemary D. Higgins, for the Follow-Up Study of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research NetworkPediatrics May 2018, 141 (5) e20173091; DOI: 10.1542/peds.2017-3091
In this study, we evaluate the full spectrum of NDI in a contemporary cohort of preterm children, including milder degrees of impairment.
- Open AccessVariability of Very Low Birth Weight Infant Outcome and Practice in Swiss and US Neonatal UnitsMark Adams, Dirk Bassler, Hans Ulrich Bucher, Matthias Roth-Kleiner, Thomas M. Berger, Julia Braun, Milo Alan Puhan, Erika Edwards, Roger Soll, Viktor Von Wyl, for the Swiss Neonatal Network and the Vermont Oxford NetworkPediatrics May 2018, 141 (5) e20173436; DOI: 10.1542/peds.2017-3436
In this study, we reveal robust, survival-bias independent outcome variability between Swiss and US neonatal units by using multivariable propensity score-matched analyses. The Swiss neonatal units follow established evidence closer.
- Open AccessHip Synovial Fluid Cell Counts in Children From a Lyme Disease Endemic AreaArianna H. Dart, Kenneth A. Michelson, Paul L. Aronson, Aris C. Garro, Thomas J. Lee, Kimberly M. Glerum, Peter A. Nigrovic, Mininder S. Kocher, Richard G. Bachur, Lise E. NigrovicPediatrics May 2018, 141 (5) e20173810; DOI: 10.1542/peds.2017-3810
Synovial fluid WBC counts alone do not help to distinguish between patients with septic and Lyme disease hip monoarthritis.
- Open AccessSafety and Immunogenicity of a Recombinant Influenza Vaccine: A Randomized TrialLisa M. Dunkle, Ruvim Izikson, Peter A. Patriarca, Karen L. Goldenthal, Manon Cox, John J. TreanorPediatrics May 2018, 141 (5) e20173021; DOI: 10.1542/peds.2017-3021
Recombinant HA provided better protection than the inactivated influenza vaccine in adults ≥50 years old but lower immunogenicity in children <5 years old. In subjects 6 to 17 years old, immunogenicity was comparable.
- Open AccessPerceptions of Health Care Transition Care Coordination in Patients With Chronic IllnessMonika Lemke, Rachel Kappel, Robert McCarter, Lawrence D’Angelo, Lisa K. TuchmanPediatrics May 2018, 141 (5) e20173168; DOI: 10.1542/peds.2017-3168
With this study, we support the effectiveness of HCT CC by improved perceptions of chronic illness care quality.
- Open AccessDevelopmental Trajectory of Language From 2 to 13 Years in Children Born Very PretermThi-Nhu-Ngoc Nguyen, Megan Spencer-Smith, Diana Zannino, Alice Burnett, Shannon E. Scratch, Leona Pascoe, Rachel Ellis, Jeanie Cheong, Deanne Thompson, Terrie Inder, Lex W. Doyle, Peter J. AndersonPediatrics May 2018, 141 (5) e20172831; DOI: 10.1542/peds.2017-2831
In this prospective longitudinal study of children born VP or term, the authors examined language functioning at 13 years of age and language development from the age of 2 years.
- Open AccessA Modified Algorithm for Critical Congenital Heart Disease Screening Using Pulse OximetryChristina L. Diller, Michael S. Kelleman, Kenneth G. Kupke, Sharon C. Quary, Lazaros K. Kochilas, Matthew E. OsterPediatrics May 2018, 141 (5) e20174065; DOI: 10.1542/peds.2017-4065
In this study, we show the results of CCHD screening using pulse oximetry at a tertiary birth hospital and the impact of a modified screening algorithm.
- Open AccessNeurobehavioral Outcomes 11 Years After Neonatal Caffeine Therapy for Apnea of PrematurityInes M. Mürner-Lavanchy, Lex W. Doyle, Barbara Schmidt, Robin S. Roberts, Elizabeth V. Asztalos, Lorrie Costantini, Peter G. Davis, Deborah Dewey, Judy D’Ilario, Ruth E. Grunau, Diane Moddemann, Harvey Nelson, Arne Ohlsson, Alfonso Solimano, Win Tin, Peter J. Anderson, for the Caffeine for Apnea of Prematurity (CAP) Trial GroupPediatrics May 2018, 141 (5) e20174047; DOI: 10.1542/peds.2017-4047
Neonatal caffeine therapy for apnea of prematurity in very low birth weight infants has long-term benefits for visuomotor, visuoperceptual, and visuospatial abilities.
- Open AccessNeighborhood Child Opportunity and Individual-Level Pediatric Acute Care Use and DiagnosesEllen E. Kersten, Nancy E. Adler, Laura Gottlieb, Douglas P. Jutte, Sarah Robinson, Katrina Roundfield, Kaja Z. LeWinnPediatrics May 2018, 141 (5) e20172309; DOI: 10.1542/peds.2017-2309
By linking individual-level health care records and a composite neighborhood-level index, we examine the associations between neighborhood child opportunity and pediatric acute care use.
- Open AccessInfant Pulmonary Function Testing and Phenotypes in Severe Bronchopulmonary DysplasiaEdward G. Shepherd, Brian J. Clouse, Kathryn A. Hasenstab, Swetha Sitaram, Daniel T. Malleske, Leif D. Nelin, Sudarshan R. JadcherlaPediatrics May 2018, 141 (5) e20173350; DOI: 10.1542/peds.2017-3350
Using iPFT data, this study demonstrates 3 distinct phenotypes in sBPD, with the unexpected finding that 9% had exclusively restrictive disease.
- Open AccessUnmet Rehabilitation Needs After Hospitalization for Traumatic Brain InjuryMolly M. Fuentes, Jin Wang, Juliet Haarbauer-Krupa, Keith Owen Yeates, Dennis Durbin, Mark R. Zonfrillo, Kenneth M. Jaffe, Nancy Temkin, David Tulsky, Hilary Bertisch, Frederick P. RivaraPediatrics May 2018, 141 (5) e20172859; DOI: 10.1542/peds.2017-2859
In this multicenter study, we investigate dysfunction and unmet need for rehabilitation and educational services in children after hospitalization for TBI.
- Open AccessExternal Validation of the PediBIRN Clinical Prediction Rule for Abusive Head TraumaHelena Pfeiffer, Anne Smith, Alison Mary Kemp, Laura Elizabeth Cowley, John A. Cheek, Stuart R. Dalziel, Meredith L. Borland, Sharon O’Brien, Megan Bonisch, Jocelyn Neutze, Ed Oakley, Louise Crowe, Stephen J. C. Hearps, Mark D. Lyttle, Silvia Bressan, Franz E. Babl, on behalf of the Paediatric Research in Emergency Department International Collaborative (PREDICT)Pediatrics May 2018, 141 (5) e20173674; DOI: 10.1542/peds.2017-3674
In this study, we externally validate a CPR aiding detection of AHT in admitted young children.
- Open AccessRelevance of Abusive Head Trauma to Intracranial Hemorrhages and Bleeding DisordersJames D. Anderst, Shannon L. Carpenter, Rodney Presley, Molly Curtin Berkoff, Allison P. Wheeler, Robert F. Sidonio, J. Michael SouciePediatrics May 2018, 141 (5) e20173485; DOI: 10.1542/peds.2017-3485
With this study, we identify the prevalences and probabilities of ICH and SDH in association with or without trauma in young children with bleeding disorders.
- Open AccessMortality After Pediatric Arterial Ischemic StrokeLauren A. Beslow, Michael M. Dowling, Sahar M.A. Hassanein, John K. Lynch, Dimitrios Zafeiriou, Lisa R. Sun, Ilona Kopyta, Luigi Titomanlio, Anneli Kolk, Anthony Chan, Jose Biller, Eric F. Grabowski, Abdalla A. Abdalla, Mark T. Mackay, Gabrielle deVeber, on behalf of the International Pediatric Stroke Study InvestigatorsPediatrics May 2018, 141 (5) e20174146; DOI: 10.1542/peds.2017-4146
We report the in-hospital mortality rate and identify risk factors among 915 neonates and 2273 children with AIS enrolled in an international registry.
- Open AccessUropathogens and Pyuria in Children With Neurogenic BladdersCatherine S. Forster, Nader Shaikh, Alejandro Hoberman, Elizabeth JacksonPediatrics May 2018, 141 (5) e20173006; DOI: 10.1542/peds.2017-3006
In this study, we examine the relationship between both leukocyte esterase and pyuria and specific uropathogens in children with neurogenic bladders.
- Open AccessA Multicomponent Early Intervention Program and Trajectories of Behavior, Cognition, and HealthSylvana M. Côté, Massimiliano Orri, Richard E. Tremblay, Orla DoylePediatrics May 2018, 141 (5) e20173174; DOI: 10.1542/peds.2017-3174
With this study, we described the impact of a 5-year prenatally commencing multicomponent early intervention program on children’s developmental trajectory of behavior, cognition, and health service use.
- Open AccessThe Grief of Mothers After the Sudden Unexpected Death of Their InfantsRichard D. Goldstein, Ruth I. Lederman, Wendy G. Lichtenthal, Sue E. Morris, Melanie Human, Amy J. Elliott, Deb Tobacco, Jyoti Angal, Hein Odendaal, Hannah C. Kinney, Holly G. Prigerson, for the PASS NetworkPediatrics May 2018, 141 (5) e20173651; DOI: 10.1542/peds.2017-3651
Using a standardized metric on a well-characterized sample, we document high, sustained levels of pathological grief in mothers after SIDS and identify potential screening targets.
- Open AccessReading Aloud, Play, and Social-Emotional DevelopmentAlan L. Mendelsohn, Carolyn Brockmeyer Cates, Adriana Weisleder, Samantha Berkule Johnson, Anne M. Seery, Caitlin F. Canfield, Harris S. Huberman, Benard P. DreyerPediatrics May 2018, 141 (5) e20173393; DOI: 10.1542/peds.2017-3393
In an RCT of the VIP, it was demonstrated that pediatric promotion of reading aloud and play resulted in reduced hyperactivity at school entry.
- Open AccessTiming and Location of Emergency Department RevisitsKenneth A. Michelson, Todd W. Lyons, Richard G. Bachur, Michael C. Monuteaux, Jonathan A. FinkelsteinPediatrics May 2018, 141 (5) e20174087; DOI: 10.1542/peds.2017-4087
Measuring pediatric revisits to the same ED significantly underestimates total revisits and is more common in departments with fewer annual pediatric visits.
- Open AccessReducing Variations in Neonatal Outcomes: Look at Practices, Systems, and the PatientJames J. Cummings, Neil MarlowPediatrics May 2018, 141 (5) e20180402; DOI: 10.1542/peds.2018-0402
From the American Academy of Pediatrics
- Open AccessInterpretation of Do Not Attempt Resuscitation Orders for Children Requiring Anesthesia and SurgeryMary E. Fallat, Courtney Hardy, SECTION ON SURGERY, SECTION ON ANESTHESIOLOGY AND PAIN MEDICINE, COMMITTEE ON BIOETHICSPediatrics May 2018, 141 (5) e20180598; DOI: 10.1542/peds.2018-0598
- Open AccessSchool Bus Transportation of Children With Special Health Care NeedsJoseph O’Neil, Benjamin D. Hoffman, COUNCIL ON INJURY, VIOLENCE, AND POISON PREVENTIONPediatrics May 2018, 141 (5) e20180513; DOI: 10.1542/peds.2018-0513
- Open AccessBeyond Mental Health Crisis Stabilization in Emergency Departments and Acute Care HospitalsStephanie K. Doupnik, Jeremy Esposito, Jane LavellePediatrics May 2018, 141 (5) e20173059; DOI: 10.1542/peds.2017-3059
- Open Access“A Guide to Gutsy Living”: Patient-Driven Development of a Pediatric Ostomy ToolkitJennie G. David, Alexander Jofriet, Michael Seid, Peter A. Margolis, for the ImproveCareNow Pediatric IBD Learning Health SystemPediatrics May 2018, 141 (5) e20172789; DOI: 10.1542/peds.2017-2789
- Open AccessThe Role of Pediatric Trainees in Addressing Oral Health Disparities in ChildrenMickey Emmanuel, Lindsay Thompson, Frank CatalanottoPediatrics May 2018, 141 (5) e20174265; DOI: 10.1542/peds.2017-4265
- Open AccessPreventive Behavioral Health Programs in Primary Care: A Systematic ReviewCourtney M. Brown, Whitney J. Raglin Bignall, Robert T. AmmermanPediatrics May 2018, 141 (5) e20170611; DOI: 10.1542/peds.2017-0611
In this review, we identify remaining gaps in the literature on the effectiveness and readiness for scale-up of behavioral health programs in the primary care setting.
- Open AccessImaging in Pediatric Concussion: A Systematic ReviewJulia Schmidt, Kathryn S. Hayward, Katlyn E. Brown, Jill G. Zwicker, Jennie Ponsford, Paul van Donkelaar, Shelina Babul, Lara A. BoydPediatrics May 2018, 141 (5) e20173406; DOI: 10.1542/peds.2017-3406
In this article, we systematically review evidence regarding imaging in pediatric concussion.
- Open AccessAllergen-Specific Immunotherapy in the Treatment of Pediatric Asthma: A Systematic ReviewJessica L. Rice, Gregory B. Diette, Catalina Suarez-Cuervo, Emily P. Brigham, Sandra Y. Lin, Murugappan Ramanathan, Karen A. Robinson, Antoine AzarPediatrics May 2018, 141 (5) e20173833; DOI: 10.1542/peds.2017-3833
This is an updated systematic review of allergen-specific immunotherapy for the treatment of pediatric asthma.
- Open AccessInpatient Quality Improvement Interventions for Asthma: A Meta-analysisKavita Parikh, Susan Keller, Shawn RalstonPediatrics May 2018, 141 (5) e20173334; DOI: 10.1542/peds.2017-3334
In this study, we will review the literature for asthma interventions initiated in the inpatient setting and assess the impact of these interventions to reduce subsequent health care use.
State-of-the-Art Review Article
- Open AccessAntibiotic Allergy in PediatricsAllison Eaddy Norton, Katherine Konvinse, Elizabeth J. Phillips, Ana Dioun BroylesPediatrics May 2018, 141 (5) e20172497; DOI: 10.1542/peds.2017-2497
In this review, we will provide pediatricians with an educational toolbox to improve their diagnosis and evaluation of antibiotic allergy in children on the basis of current literature.
- Open AccessThe Tobacco Industry and Children’s RightsYvette van der Eijk, Stella A. Bialous, Stanton GlantzPediatrics May 2018, 141 (5) e20174106; DOI: 10.1542/peds.2017-4106
Using previously secret tobacco industry documents, we show how tobacco companies formed partnerships with UNICEF to undermine UNICEF’s involvement in tobacco control.
- Open AccessAn Adaptable Pediatrics Faculty Mentoring ModelJoan M. Cranmer, Amy M. Scurlock, Rachel B. Hale, Wendy L. Ward, Parthak Prodhan, Judith L. Weber, Patrick H. Casey, Richard F. JacobsPediatrics May 2018, 141 (5) e20173202; DOI: 10.1542/peds.2017-3202
We describe all aspects of an effective, successful, and adaptable FMP model to mitigate faculty burnout and enhance academic success.
- Open AccessShould a Teenager Be Allowed to Leave the Hospital AMA to Attend His Father’s Funeral?Thomas Kania, Melissa Schafer, Amy E. Caruso Brown, Robert S. Olick, John D. LantosPediatrics May 2018, 141 (5) e20170902; DOI: 10.1542/peds.2017-0902
A teenager needs urgent medical treatment, but it will prevent him from attending his father’s funeral. His mother supports his decision. What should his doctors do?
- Open AccessReducing Electrolyte Testing in Hospitalized Children by Using Quality Improvement MethodsMichael J. Tchou, Sonya Tang Girdwood, Benjamin Wormser, Meifawn Poole, Stephanie Davis-Rodriguez, J. Timothy Caldwell, Lauren Shannon, Philip A. Hagedorn, Eric Biondi, Jeffrey Simmons, Jeffrey Anderson, Patrick W. BradyPediatrics May 2018, 141 (5) e20173187; DOI: 10.1542/peds.2017-3187
With our quality improvement initiative, we improved the value of patient care by reducing overuse of electrolyte testing across hospital medicine services.
- Open AccessFacilitating the Timely Discharge of Well Newborns by Using Quality Improvement MethodsNicole T. Rochester, Laurie P. Banach, Wendy Hoffner, Deena Zeltser, Phyllis Lewis, Elizabeth Seelbach, Sandra CuzziPediatrics May 2018, 141 (5) e20170872; DOI: 10.1542/peds.2017-0872
In this study, we evaluate the use of a discharge checklist to improve the timely discharge of well newborns in a hospital with a high delivery volume.
- Open AccessImproving Anaphylaxis Care: The Impact of a Clinical PathwayJuhee Lee, Bonnie Rodio, Jane Lavelle, Megan Ott Lewis, Rachel English, Sarah Hadley, Jennifer Molnar, Cynthia Jacobstein, Antonella Cianferoni, Jonathan Spergel, Lisa Zielinski, Nicholas Tsarouhas, Terri Brown-WhitehornPediatrics May 2018, 141 (5) e20171616; DOI: 10.1542/peds.2017-1616
By revising an ED anaphylaxis clinical pathway and decreasing the recommended length of observation, we safely reduced admissions by nearly 60% for anaphylaxis patients.
- Open AccessAn 18-Year-Old With Acute-on-Chronic Abdominal PainMark H. Corden, Jamie Frediani, Frank Xu, Quin Y. Liu, Shiu-Yi Emily Chen, D. Montgomery Bissell, Kathleen OstromPediatrics May 2018, 141 (5) e20171332; DOI: 10.1542/peds.2017-1332
An unusual cause of recurrent abdominal pain in an adolescent woman.
- Open AccessRelapsing Pityriasis Rosea With HHV-7 Reactivation in an 11-Year-Old GirlIlka Engelmann, Judith Ogiez, Lucie Ogiez, Enagnon Kazali Alidjinou, Mouna Lazrek, Anny Dewilde, Didier HoberPediatrics May 2018, 141 (5) e20173179; DOI: 10.1542/peds.2017-3179
We describe an 11-year-old girl with recurrent episodes of PR over several years that was associated with HHV-7 DNA detection.
- Open AccessCopper Deficiency Anemia and Neutropenia Due to Ketogenic DietAlan ChinPediatrics May 2018, 141 (5) e20173286; DOI: 10.1542/peds.2017-3286
Copper deficiency is an uncommon cause of anemia and neutropenia and can present because of the restrictions of a ketogenic diet.
- Open AccessSuccessful Management of Chylothorax With Etilefrine: Case Report in 2 Pediatric PatientsGysella Muniz, Jennifer Hidalgo-Campos, Maria del Carmen Valdivia-Tapia, Nader Shaikh, Nilton Yhuri CarreazoPediatrics May 2018, 141 (5) e20163309; DOI: 10.1542/peds.2016-3309
This is the first case report in which we review the clinical course of 2 infants with postsurgical chylothorax who were successfully treated with etilefrine after failing conservative therapy.
- Open AccessSharara-Chami et al. Combination Analgesia for Neonatal Circumcision: A Randomized Controlled Trial. Pediatrics. 2017;140(6):e20171935Pediatrics May 2018, 141 (5) e20180500; DOI: 10.1542/peds.2018-0500
Letters to the Editors
- Open AccessAuthors’ Response Sedation Safety Has Many Perspectives, and the Discussion is OngoingHelen H. Lee, Erika A. Blacksher, Wylie BurkePediatrics May 2018, 141 (5) e20180257B; DOI: 10.1542/peds.2018-0257B
- Open AccessConcerns About the Study “Congenital Heart Surgery on In-Hospital Mortality in Trisomy 13 and 18”Yoshihiko Shitara, Yuki Naruse, Rie MatsushitaPediatrics May 2018, 141 (5) e20180400A; DOI: 10.1542/peds.2018-0400A