PURPOSE OF THE STUDY.
To review the effect of fish intake during pregnancy or infancy on allergic outcomes.
This was a meta-analysis of 1 randomized controlled trial (RCT) and 13 prospective cohort studies. The researchers conducting the RCT enrolled infants at risk for atopy (at least 1 first-degree relative affected by atopy, asthma, or allergy by self-report). The researchers conducting the cohort studies enrolled healthy pregnant women or infants without selection for atopic disease. Studies were conducted in North America, Europe, and Asia.
PubMed, Embase, and the Cochrane Central Register of Controlled Trials were searched for records …