A, CD case-finding by asking for CD-associated symptoms a in questionnaires returned by 7054 children in the general population. B, CD case-finding by asking for CD-associated symptoms a and/or conditions b in questionnaires returned by both 6226 children and their parents. a Having suffered from any of the symptoms (tiredness, poor appetite, nausea, stomach ache, upset stomach, abdominal gas, bloating, lactose intolerance, hard stools, loose stools) often or always during the past 6 months. b Presence of any of the diseases (anemia, type 1 diabetes, rheumatic disease, thyroid disease, inflammatory bowel disease, vitiligo, alopecia areata, dermatitis herpetiformis, trisomy 21, or Turner syndrome) and/or CD reported as present in the child’s biological mother, father, and/or siblings.
↵a Self-reported symptoms present often or always during the past 6 months.
↵b Internal nonresponses for non-CD children ranged from n = 126 to n = 285; for CD cases they ranged from n = 1 to n = 7. Proportions were calculated by using the total number of responses for each item as the denominator in the different groups. Thus, internal nonresponses were excluded for each item.
↵c OR of being a screening-detected CD case if symptom(s) present compared with if symptom(s) not present (with 95% CI) calculated by logistic regression, adjusted for gender.