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Discover Pediatric Collections on COVID-19 and Racism and Its Effects on Pediatric Health

American Academy of Pediatrics
Article

Autistic Traits in Children With and Without ADHD

Amelia Kotte, Gagan Joshi, Ronna Fried, Mai Uchida, Andrea Spencer, K. Yvonne Woodworth, Tara Kenworthy, Stephen V. Faraone and Joseph Biederman
Pediatrics September 2013, 132 (3) e612-e622; DOI: https://doi.org/10.1542/peds.2012-3947
Amelia Kotte
aClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts;
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Gagan Joshi
bDepartment of Psychiatry, Harvard Medical School and
cAlan & Lorraine Bressler Center, Massachusetts General Hospital, Boston, Massachusetts; and
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Ronna Fried
aClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts;
bDepartment of Psychiatry, Harvard Medical School and
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Mai Uchida
aClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts;
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Andrea Spencer
aClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts;
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K. Yvonne Woodworth
aClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts;
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Tara Kenworthy
aClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts;
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Stephen V. Faraone
dDepartments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York
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Joseph Biederman
aClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts;
bDepartment of Psychiatry, Harvard Medical School and
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Abstract

OBJECTIVE: To assess the implications of autistic traits (ATs) in youth with attention-deficit/hyperactivity disorder (ADHD) without a diagnosis of autism.

METHODS: Participants were youth with (n = 242) and without (n = 227) ADHD and controls without ADHD in whom a diagnosis of autism was exclusionary. Assessment included measures of psychiatric, psychosocial, educational, and cognitive functioning. ATs were operationalized by using the withdrawn + social + thought problems T scores from the Child Behavior Checklist.

RESULTS: A positive AT profile was significantly overrepresented among ADHD children versus controls (18% vs 0.87%; P < .001). ADHD children with the AT profile were significantly more impaired than control subjects in psychopathology, interpersonal, school, family, and cognitive domains.

CONCLUSIONS: A substantial minority of ADHD children manifests ATs, and those exhibiting ATs have greater severity of illness and dysfunction.

  • ADD
  • ADHD
  • attention deficit disorder
  • attention-deficit/hyperactivity disorder
  • AT
  • autistic traits
  • autism traits
  • comorbidity
  • social disability
  • Abbreviations:
    ADD —
    attention deficit disorder
    ADHD —
    attention-deficit/hyperactivity disorder
    ASD —
    autism spectrum disorder
    ATs —
    autistic traits
    CBCL —
    Child Behavior Checklist
    DSM-III-R —
    Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition
    MGH —
    Massachusetts General Hospital
    OR —
    odds ratio
    SAICA —
    Social Adjustment Inventory for Children and Adolescents
    SES —
    socioeconomic status
    WISC-R —
    Wechsler Intelligence Scale for Children–Revised
    • Accepted June 26, 2013.
    • Copyright © 2013 by the American Academy of Pediatrics

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    Pediatrics
    Vol. 132, Issue 3
    1 Sep 2013
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    Autistic Traits in Children With and Without ADHD
    Amelia Kotte, Gagan Joshi, Ronna Fried, Mai Uchida, Andrea Spencer, K. Yvonne Woodworth, Tara Kenworthy, Stephen V. Faraone, Joseph Biederman
    Pediatrics Sep 2013, 132 (3) e612-e622; DOI: 10.1542/peds.2012-3947

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    Autistic Traits in Children With and Without ADHD
    Amelia Kotte, Gagan Joshi, Ronna Fried, Mai Uchida, Andrea Spencer, K. Yvonne Woodworth, Tara Kenworthy, Stephen V. Faraone, Joseph Biederman
    Pediatrics Sep 2013, 132 (3) e612-e622; DOI: 10.1542/peds.2012-3947
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    Subjects

    • Developmental/Behavioral Pediatrics
      • Developmental/Behavioral Pediatrics
      • Attention-Deficit/Hyperactivity Disorder (ADHD)
      • Autism/ASD

    Keywords

    • ADD
    • ADHD
    • attention deficit disorder
    • attention-deficit/hyperactivity disorder
    • AT
    • autistic traits
    • autism traits
    • comorbidity
    • social disability
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