Skip to main content

Advertising Disclaimer »

Main menu

  • Journals
    • Pediatrics
    • Hospital Pediatrics
    • Pediatrics in Review
    • NeoReviews
    • AAP Grand Rounds
    • AAP News
  • Authors/Reviewers
    • Submit Manuscript
    • Author Guidelines
    • Reviewer Guidelines
    • Open Access
    • Editorial Policies
  • Content
    • Current Issue
    • Online First
    • Archive
    • Blogs
    • Topic/Program Collections
    • AAP Meeting Abstracts
  • Pediatric Collections
    • COVID-19
    • Racism and Its Effects on Pediatric Health
    • More Collections...
  • AAP Policy
  • Supplements
    • Supplements
    • Publish Supplement
  • Multimedia
    • Video Abstracts
    • Pediatrics On Call Podcast
  • Subscribe
  • Alerts
  • Careers
  • Other Publications
    • American Academy of Pediatrics

User menu

  • Log in
  • My Cart

Search

  • Advanced search
American Academy of Pediatrics

AAP Gateway

Advanced Search

AAP Logo

  • Log in
  • My Cart
  • Journals
    • Pediatrics
    • Hospital Pediatrics
    • Pediatrics in Review
    • NeoReviews
    • AAP Grand Rounds
    • AAP News
  • Authors/Reviewers
    • Submit Manuscript
    • Author Guidelines
    • Reviewer Guidelines
    • Open Access
    • Editorial Policies
  • Content
    • Current Issue
    • Online First
    • Archive
    • Blogs
    • Topic/Program Collections
    • AAP Meeting Abstracts
  • Pediatric Collections
    • COVID-19
    • Racism and Its Effects on Pediatric Health
    • More Collections...
  • AAP Policy
  • Supplements
    • Supplements
    • Publish Supplement
  • Multimedia
    • Video Abstracts
    • Pediatrics On Call Podcast
  • Subscribe
  • Alerts
  • Careers

Discover Pediatric Collections on COVID-19 and Racism and Its Effects on Pediatric Health

American Academy of Pediatrics
SUPPLEMENT ARTICLE

Complementary and Alternative Medicine Use in a Large Pediatric Autism Sample

James M. Perrin, Daniel L. Coury, Susan L. Hyman, Lynn Cole, Ann M. Reynolds and Traci Clemons
Pediatrics November 2012, 130 (Supplement 2) S77-S82; DOI: https://doi.org/10.1542/peds.2012-0900E
James M. Perrin
aDepartment of Pediatrics, Harvard Medical School, MassGeneral Hospital for Children, Boston, Massachusetts;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daniel L. Coury
bNationwide Children’s Hospital, The Ohio State University School of Medicine, Columbus, Ohio;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Susan L. Hyman
cGolisano Children’s Hospital, University of Rochester School of Medicine, Rochester, New York;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lynn Cole
cGolisano Children’s Hospital, University of Rochester School of Medicine, Rochester, New York;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ann M. Reynolds
dChildren’s Hospital Colorado, University of Colorado, Aurora, Colorado; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Traci Clemons
eEMMES Corporation, Rockville, Maryland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Comments
Loading

Article Figures & Data

Tables

    • View popup
    TABLE 1

    Characteristics of ATN Participants According to CAM Usage

    CharacteristicNo CAM UsageaAny CAM UsageTotal
    Age, y
     2–51274 (56)    514 (57)1788
     6–11765 (34)    297 (33)1062
     12–18238 (10)    85 (9)323
    Gender
     Male1924 (85)    747 (83)2671
     Female353 (15)    149 (17)502
    ASD
     Autism1481 (65)    633 (71)2114
     Asperger’s215 (9)    74 (8)289
     PDD-NOS581 (26)    189 (21)770
    Caregiver(s)’ highest level of education
     High school graduate or less360 (17)    69 (8)429
     Some college619 (29)    197 (23)816
     College graduate598 (28)    311 (36)909
     Postgraduate work573 (27)    275 (32)848
     Missing—    —171
    Race
     White1738 (76)    732 (82)2470
     Black/African American195 (9)    31 (3)226
     Asian116 (5)    46 (5)162
     Other228 (10)    87 (10)315
    Ethnicity
     Hispanic or Latino origin243 (11)    64 (7)307
     Not of Hispanic or Latino origin1984 (89)    811 (93)2795
     Missing—    —71
    Parent-reported GI problems
     No1151 (52)    305 (35)1456
     Yes1064 (48)    568 (65)1632
     Missing—    —85
    Parent-reported sleep problems as measured by using the CSHQ (age <11 y)
     No566 (33)    219 (31)924
     Yes1156 (67)    477 (69)1882
     Missing—    —367
    CBCL internalizing t score
     <701632 (76)    602 (71)2234
      ≥70523 (24)    249 (29)772
    CBCL externalizing t score
     <701796 (83)    688 (81)2484
      ≥70359 (17)    163 (19)522
    CBCL total score
     <701488 (69)    538 (63)2026
      ≥70667 (31)    313 (37)980
     Missing CBCL data—    —167
    Parent-reported history of seizures
     No1916 (85)    678 (76)2594
     Yes336 (15)    206 (24)545
     Missing34
    Reported psychotropic medication usage
     No1387 (73)    547 (73)1934
     Yes516 (27)    206 (27)722
     Missing——517
    • Data are presented as number (%).

    • ↵a Percentages may not add to 100 due to rounding.

    • View popup
    TABLE 2

    Rates of Specific CAM Usage

    CharacteristicN
    Any CAM896
    Special diets548
    Gluten-free diet249
    Casein-free diet289
    No processed sugars69
    No sugars or salicylates28
    Feingold diet14
    Other specified special diet293
    Other CAM643
    Other vitamin supplements413
    Probiotics274
    Essential fatty acids171
    Digestive enzymes116
    Higher dosing vitamin B6 and magnesium99
    Chiropractic77
    Amino acids59
    Antifungals58
    Glutathione33
    Chelation19
    Hyperbaric oxygen12
    Acupuncture10
    Sulfation7
    Other specified CAM173
    • View popup
    TABLE 3

    Associations (ORs) Between Use of Any CAM and Subgroup Categories of Special Diets and “Other” CAM

    FactorExposureAny CAM (n = 896)Special Diets (n= 548)aOther CAM (n = 643)a
    A Versus B
    Gender      Male       Female0.920.960.88
    ASD      Asperger’s       Autism0.81*0.51*0.91
          PDD-NOS       Autism0.76*0.70*0.77*
    Parent-reported GI problems      Yes       No2.01*2.46*1.91*
    Parent-reported sleep problems as measured by using the CSHQ      Yes       No1.071.080.96
    Parent-reported history of seizures      Yes       No1.76*2.16*1.71*
    CBCL internalizing T score      Yes       No1.29*1.39*1.19*
    CBCL externalizing T score      Yes       No1.19*1.29*1.01
    CBCL total score      Yes       No1.30*1.42*1.14*
    Reported psychotropic medication usage      Yes       No1.010.79*1.14
    • ↵a Compared with the no CAM usage group.

    • ↵* Nominally significant, P < .20.

    • View popup
    TABLE 4

    Multivariable Associations (ORs) Between Use of Any CAM, Special Diets, or Other CAM

    FactorExposureAny CAMa (n = 896)Special Dietsa,b (n = 548)Other CAMa,b (n = 643)
    A Versus B
    ASD     Asperger’s     Autism0.62 (0.46–0.84)0.44 (0.28–0.69)0.72 (0.52–1.00)
         PDD-NOS     Autism0.66 (0.54–0.82)0.65 (0.49–0.85)0.67 (0.53–0.84)
    Parent-reported GI problems     Yes     No1.88 (1.57–2.25)2.38 (1.86–3.05)1.82 (1.50–2.22)
    CBCL total score     Yes     No1.29 (1.06–1.56)1.34 (1.04–1.72)NSc
    Parent-reported history of seizures     Yes     No1.58 (1.27–1.96)1.97 (1.50–2.59)1.66 (1.30–2.10)
    Reported psychotropic medication usage     Yes     NoNSc0.69 (0.52–0.91)NSc
    • ↵a ORs (95% confidence intervals) from stage 3 model, comparing the outcome with no CAM usage.

    • ↵b Compared with the no CAM usage group.

    • ↵c Non significant differences.

PreviousNext
Back to top

Advertising Disclaimer »

In this issue

Pediatrics
Vol. 130, Issue Supplement 2
1 Nov 2012
  • Table of Contents
  • Index by author
View this article with LENS
PreviousNext
Email Article

Thank you for your interest in spreading the word on American Academy of Pediatrics.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Complementary and Alternative Medicine Use in a Large Pediatric Autism Sample
(Your Name) has sent you a message from American Academy of Pediatrics
(Your Name) thought you would like to see the American Academy of Pediatrics web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Request Permissions
Article Alerts
Log in
You will be redirected to aap.org to login or to create your account.
Or Sign In to Email Alerts with your Email Address
Citation Tools
Complementary and Alternative Medicine Use in a Large Pediatric Autism Sample
James M. Perrin, Daniel L. Coury, Susan L. Hyman, Lynn Cole, Ann M. Reynolds, Traci Clemons
Pediatrics Nov 2012, 130 (Supplement 2) S77-S82; DOI: 10.1542/peds.2012-0900E

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Complementary and Alternative Medicine Use in a Large Pediatric Autism Sample
James M. Perrin, Daniel L. Coury, Susan L. Hyman, Lynn Cole, Ann M. Reynolds, Traci Clemons
Pediatrics Nov 2012, 130 (Supplement 2) S77-S82; DOI: 10.1542/peds.2012-0900E
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Print
Download PDF
Insight Alerts
  • Table of Contents

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Comments

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Service Use Classes Among School-aged Children From the Autism Treatment Network Registry
  • Identification, Evaluation, and Management of Children With Autism Spectrum Disorder
  • Do We Have Evidence for Dietary and Nutritional Interventions for Autism Spectrum Disorder?
  • Ethical Implications for Providers Regarding Cannabis Use in Children With Autism Spectrum Disorders
  • Pediatric Integrative Medicine
  • Nutritional and Dietary Interventions for Autism Spectrum Disorder: A Systematic Review
  • Iodine Deficiency and Hypothyroidism From Voluntary Diet Restrictions in the US: Case Reports
  • The Autism Speaks Autism Treatment Network Registry Data: Opportunities for Investigators
  • CAM Use in Children With Recurrent Headaches
  • Complementary, Holistic, and Integrative Medicine: Autism Spectrum Disorder and Gluten- and Casein-Free Diet
  • Google Scholar

More in this TOC Section

  • Part 4: Pediatric Basic and Advanced Life Support 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
  • Pediatric Life Support 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
  • Part 5: Neonatal Resuscitation 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
Show more Supplement Articles

Similar Articles

Subjects

  • Developmental/Behavioral Pediatrics
    • Developmental/Behavioral Pediatrics
    • Autism/ASD

Keywords

  • autism spectrum disorders
  • complementary and alternative medicine
  • Journal Info
  • Editorial Board
  • Editorial Policies
  • Overview
  • Licensing Information
  • Authors/Reviewers
  • Author Guidelines
  • Submit My Manuscript
  • Open Access
  • Reviewer Guidelines
  • Librarians
  • Institutional Subscriptions
  • Usage Stats
  • Support
  • Contact Us
  • Subscribe
  • Resources
  • Media Kit
  • About
  • International Access
  • Terms of Use
  • Privacy Statement
  • FAQ
  • AAP.org
  • shopAAP
  • Follow American Academy of Pediatrics on Instagram
  • Visit American Academy of Pediatrics on Facebook
  • Follow American Academy of Pediatrics on Twitter
  • Follow American Academy of Pediatrics on Youtube
  • RSS
American Academy of Pediatrics

© 2021 American Academy of Pediatrics