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Discover Pediatric Collections on COVID-19 and Racism and Its Effects on Pediatric Health

American Academy of Pediatrics

A statement of reaffirmation for this policy was published at

  • e20162595
From the American Academy of PediatricsTechnical Report

The Lifelong Effects of Early Childhood Adversity and Toxic Stress

Jack P. Shonkoff, Andrew S. Garner, THE COMMITTEE ON PSYCHOSOCIAL ASPECTS OF CHILD AND FAMILY HEALTH, COMMITTEE ON EARLY CHILDHOOD, ADOPTION, AND DEPENDENT CARE, AND SECTION ON DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, Benjamin S. Siegel, Mary I. Dobbins, Marian F. Earls, Andrew S. Garner, Laura McGuinn, John Pascoe and David L. Wood
Pediatrics January 2012, 129 (1) e232-e246; DOI: https://doi.org/10.1542/peds.2011-2663
Jack P. Shonkoff
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Andrew S. Garner
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Benjamin S. Siegel
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Mary I. Dobbins
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Marian F. Earls
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Andrew S. Garner
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Laura McGuinn
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John Pascoe
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David L. Wood
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    FIGURE 1

    The basic science of pediatrics. An emerging, multidisciplinary science of development supports an EBD framework for understanding the evolution of human health and disease across the life span. In recent decades, epidemiology, developmental psychology, and longitudinal studies of early childhood interventions have demonstrated significant associations (hashed red arrow) between the ecology of childhood and a wide range of developmental outcomes and life course trajectories. Concurrently, advances in the biological sciences, particularly in developmental neuroscience and epigenetics, have made parallel progress in beginning to elucidate the biological mechanisms (solid arrows) underlying these important associations. The convergence of these diverse disciplines defines a promising new basic science of pediatrics.

  • FIGURE 2
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    FIGURE 2

    An ecobiodevelopmental framework for early childhood policies and programs. This was adapted from ref 1. See text for details.

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Pediatrics
Vol. 129, Issue 1
1 Jan 2012
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The Lifelong Effects of Early Childhood Adversity and Toxic Stress
Jack P. Shonkoff, Andrew S. Garner, THE COMMITTEE ON PSYCHOSOCIAL ASPECTS OF CHILD AND FAMILY HEALTH, COMMITTEE ON EARLY CHILDHOOD, ADOPTION, AND DEPENDENT CARE, AND SECTION ON DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, Benjamin S. Siegel, Mary I. Dobbins, Marian F. Earls, Andrew S. Garner, Laura McGuinn, John Pascoe, David L. Wood
Pediatrics Jan 2012, 129 (1) e232-e246; DOI: 10.1542/peds.2011-2663

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The Lifelong Effects of Early Childhood Adversity and Toxic Stress
Jack P. Shonkoff, Andrew S. Garner, THE COMMITTEE ON PSYCHOSOCIAL ASPECTS OF CHILD AND FAMILY HEALTH, COMMITTEE ON EARLY CHILDHOOD, ADOPTION, AND DEPENDENT CARE, AND SECTION ON DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, Benjamin S. Siegel, Mary I. Dobbins, Marian F. Earls, Andrew S. Garner, Laura McGuinn, John Pascoe, David L. Wood
Pediatrics Jan 2012, 129 (1) e232-e246; DOI: 10.1542/peds.2011-2663
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    • Abstract
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    • A New Framework for Promoting Healthy Development
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