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American Academy of Pediatrics
Case Report

Recurrent Parotitis as a Presentation of Primary Pediatric Sjögren Syndrome

Kevin Baszis, Dana Toib, Megan Cooper, Anthony French and Andrew White
Pediatrics January 2012, 129 (1) e179-e182; DOI: https://doi.org/10.1542/peds.2011-0716
Kevin Baszis
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Dana Toib
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Megan Cooper
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Anthony French
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Andrew White
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Abstract

Parotitis is a common condition seen in the pediatric population, usually as an isolated occurrence associated with viral or bacterial infection. The differential diagnosis expands when recurrent parotitis is encountered. One etiology is primary pediatric Sjögren syndrome (SS), an autoimmune condition typically associated with dryness of the eyes and mouth in adults. Pediatric patients often present with isolated recurrent bilateral parotitis, however, and we describe 4 such cases in children aged 9 to 17 years at presentation. Despite lack of ocular complaints, 3 of these patients had ocular findings on ophthalmologic exam. Our patients also exhibited classic laboratory abnormalities, including positive antinuclear antibody, SS A, and SS B antibodies; presence of rheumatoid factor; and hypergammaglobulinemia. Consideration of SS in the child with recurrent parotitis is important for timely and appropriate referral and treatment. We review the differential diagnosis of parotitis in children as well as the salient features of pediatric SS.

KEY WORDS
  • parotitis
  • Sjögren syndrome
  • Abbreviations:
    ANA —
    antinuclear antibody
    ESR —
    erythrocyte sedimentation rate
    RF —
    rheumatoid factor
    SLE —
    systemic lupus erythematosus
    SS —
    Sjögren syndrome
    • Accepted September 8, 2011.
    • Copyright © 2012 by the American Academy of Pediatrics

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    Pediatrics
    Vol. 129, Issue 1
    1 Jan 2012
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    Recurrent Parotitis as a Presentation of Primary Pediatric Sjögren Syndrome
    Kevin Baszis, Dana Toib, Megan Cooper, Anthony French, Andrew White
    Pediatrics Jan 2012, 129 (1) e179-e182; DOI: 10.1542/peds.2011-0716

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    Recurrent Parotitis as a Presentation of Primary Pediatric Sjögren Syndrome
    Kevin Baszis, Dana Toib, Megan Cooper, Anthony French, Andrew White
    Pediatrics Jan 2012, 129 (1) e179-e182; DOI: 10.1542/peds.2011-0716
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