Equimolar Nitrous Oxide/Oxygen Versus Placebo for Procedural Pain in Children: A Randomized Trial | American Academy of Pediatrics

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ethical issues
Georg Staubli

Published on: 07 June 2011

Published on: (7 June 2011)

ethical issues
Georg Staubli, Head of the emergency department
Laughing gas is a well know analgesic gas. It`s used since over 100 years. There are hundreds of studies that confirm the analgesic effect of laughing gas in combination with oxygen. I`m very suprised that a ethical committee accepted this study. As pediatrician I don`t comprehend how somebody could make such a study in our times. The question is not if laughing gas is a good analgesic drug but for what procedures it is...
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Laughing gas is a well know analgesic gas. It`s used since over 100 years. There are hundreds of studies that confirm the analgesic effect of laughing gas in combination with oxygen. I`m very suprised that a ethical committee accepted this study. As pediatrician I don`t comprehend how somebody could make such a study in our times. The question is not if laughing gas is a good analgesic drug but for what procedures it is better than others. A comparison against placebo is for me ethically not acceptable.
Conflict of Interest:
None declared
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Competing Interests: None declared.

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